Method to impact in vivo rabbit femoral cartilage with blows of quantifiable stress

Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
M S VrahasR V Baratta

Abstract

The purpose of this study was to develop a technique by which a known stress could be applied uniformly across the femoral cartilage of a rabbit as a model for the development of post-traumatic arthritis. A system to impact the cartilage was designed that consisted of an apparatus to deliver a blow of quantifiable force, a method to apply the stress uniformly over the impact area, and a way to accurately measure the impact area. The knee joints of cadaveric New Zealand White rabbits were surgically exposed with the knee flexed so that the distal femoral articular surface was perpendicular to an impactor. With the knee fixed in position, a cup containing polymethylmethacrylate bone cement was applied to create an exact contour of the femoral surface, and the cement was allowed to cure. The form was then rested on the rabbit knee, and a drop tower released a weight of known mass from a known height onto an impactor (instrumented with strain gauges to measure the compressive force) that was attached to the cup. The area of the impacted surface was determined and, with the measured force, was used to calculate an accurate estimate of the impact stress. This method can be performed under sterile conditions, and therefore it is well ...Continue Reading

Citations

Sep 2, 2014·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Richard BrillFrank W Roemer
May 11, 2012·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Frank LeuchtRolf E Brenner
Jul 9, 2005·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Guillermo E ChaconRobert Rashid
Oct 24, 2003·Journal of Orthopaedic Trauma·Joseph BorrelliRichard Hotchkiss
Mar 7, 2002·Journal of Orthopaedic Trauma·Joseph BorrelliMatthew J Silva
Jan 30, 2004·The Journal of Trauma·Martha Meaney MurrayMark S Vrahas
Jul 3, 2004·Clinical Orthopaedics and Related Research·Joseph Borrelli, William M Ricci
Jul 3, 2004·Clinical Orthopaedics and Related Research·Mark S VrahasDavid Joseph
Oct 1, 2010·Arthritis and Rheumatism·Blandine PouletAndrew A Pitsillides

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