Methods for biomimetic remineralization of human dentine: a systematic review

International Journal of Molecular Sciences
Chris Ying CaoChun Hung Chu

Abstract

This study aimed to review the laboratory methods on biomimetic remineralization of demineralized human dentine. A systematic search of the publications in the PubMed, TRIP, and Web of Science databases was performed. Titles and abstracts of initially identified publications were screened. Clinical trials, reviews, non-English articles, resin-dentine interface studies, hybrid layer studies, hybrid scaffolds studies, and irrelevant studies were excluded. The remaining papers were retrieved with full texts. Manual screening was conducted on the bibliographies of remaining papers to identify relevant articles. A total of 716 studies were found, and 690 were excluded after initial screening. Two articles were identified from the bibliographies of the remaining papers. After retrieving the full text, 23 were included in this systematic review. Sixteen studies used analogues to mimic the functions of non-collagenous proteins in biomineralization of dentine, and four studies used bioactive materials to induce apatite formation on demineralized dentine surface. One study used zinc as a bioactive element, one study used polydopamine, and another study constructed an agarose hydrogel system for biomimetic mineralization of dentine. Many ...Continue Reading

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Citations

Oct 24, 2017·Polymer Chemistry·Dakota J SuchytaMark H Schoenfisch
Jul 19, 2020·Biomimetics·Muhammad Sohail ZafarNaresh Kumar
Sep 14, 2020·Microscopy Research and Technique·Bianca Silva GomesMaristela Barbosa Portela
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Mar 12, 2020·Materials·Marta Kunert, Monika Lukomska-Szymanska
Sep 12, 2017·Journal of Dental Research·M AlkilzyC H Splieth
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Jul 25, 2017·Dental Materials : Official Publication of the Academy of Dental Materials·Michael D WeirHockin H K Xu
Aug 28, 2020·Dental Materials : Official Publication of the Academy of Dental Materials·Siying TaoJiyao Li
Jun 19, 2019·Dental Materials : Official Publication of the Academy of Dental Materials·Arndt GuentschBernd W Sigusch
Sep 27, 2020·Dental Materials : Official Publication of the Academy of Dental Materials·Ruitian ChenZhi Chen
Dec 15, 2020·ACS Biomaterials Science & Engineering·Kaushik MukherjeeJanet Moradian-Oldak

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