Methods for determination of aflatoxin M1 in milk and milk products--a review of performance characteristics

Food Additives and Contaminants
P M Scott

Abstract

Among numerous methods that have been published for determination of aflatoxin M1 in milk and milk products, the following have been selected for review of performance characteristics: methods for which interlaboratory testing has been carried out, methods proposed in support of national (Swiss) regulations following inclusion in check sample series, and methods that report detection limits for milk of less than or equal to 5 ng/l (less than or equal to 0.005 microgram/l) or less than or equal to 10 ng/kg (less than or equal to 0.01 microgram/kg) for cheese. It is practical to determine aflatoxin M1 in milk with good accuracy and precision down to low ng/l concentrations using thin-layer chromatography, high-performance liquid chromatography or enzyme-linked immunosorbent assay for quantitation. However, measurement at such low levels has not been tested by a true collaborative study. Confirmation of identity of aflatoxin M1 at low ng/l levels has also been reported. Recent evidence suggests that consideration should be given to inclusion of aflatoxin M4 in methods for aflatoxin M1.

References

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Citations

Mar 8, 2003·Food Additives and Contaminants·M L Rodríguez VelascoD Ordónez Escudero
Nov 23, 2006·Food Additives and Contaminants·Meenakshi TripathiMukul Das
May 1, 1993·The Journal of Dairy Research·C Vidal-Valverde, P Redondo
Apr 1, 1994·Pharmacology & Therapeutics·C J Bates, A Prentice
Aug 1, 1996·International Journal of Food Microbiology·R Roostita, G H Fleet
Jul 24, 2012·Journal of Dairy Science·P C B ViannaM L Gigante
Jun 1, 1990·Analytical Chemistry·J Sherma
Jun 1, 1990·Analytical Chemistry·H G Barth, B E Boyes
Sep 18, 2016·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Dahai ShaoWilson K Rumbeiha
Dec 22, 2006·Journal of Dairy Science·K AchantaK J Aryana
Jan 20, 2007·Journal of Dairy Science·G MazalM L Gigante
Feb 8, 2020·Journal of Environmental Health Science & Engineering·Mehdi HassanpourAmin Baghizadeh
Oct 24, 2009·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·A GürbayG Tekinalp

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