Methods for motion correction evaluation using 18F-FDG human brain scans on a high-resolution PET scanner

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Sune H KellerLiselotte Højgaard

Abstract

Many authors have reported the importance of motion correction (MC) for PET. Patient motion during scanning disturbs kinetic analysis and degrades resolution. In addition, using misaligned transmission for attenuation and scatter correction may produce regional quantification bias in the reconstructed emission images. The purpose of this work was the development of quality control (QC) methods for MC procedures based on external motion tracking (EMT) for human scanning using an optical motion tracking system. Two scans with minor motion and 5 with major motion (as reported by the optical motion tracking system) were selected from (18)F-FDG scans acquired on a PET scanner. The motion was measured as the maximum displacement of the markers attached to the subject's head and was considered to be major if larger than 4 mm and minor if less than 2 mm. After allowing a 40- to 60-min uptake time after tracer injection, we acquired a 6-min transmission scan, followed by a 40-min emission list-mode scan. Each emission list-mode dataset was divided into 8 frames of 5 min. The reconstructed time-framed images were aligned to a selected reference frame using either EMT or the AIR (automated image registration) software. The following 3 QC ...Continue Reading

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Citations

Aug 26, 2014·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Dean F WongAndrew G Horti
Feb 16, 2016·Current Biology : CB·Brian A AndersonSteven Yantis
Sep 26, 2012·IEEE Transactions on Medical Imaging·Oline V OlesenRasmus Larsen
May 6, 2016·Medical Physics·J M MukherjeeR Licho
Nov 3, 2015·Seminars in Nuclear Medicine·Eric SalmonRoland Hustinx
Sep 1, 2016·IEEE Transactions on Medical Imaging·Jieqing JiaoSebastien Ourselin
Nov 25, 2016·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Joonas MajuriValtteri Kaasinen
Jan 24, 2019·Physics in Medicine and Biology·Hideaki TashimaTaiga Yamaya
Aug 8, 2015·Physics in Medicine and Biology·P J SchleyerK Thielemans
Jan 6, 2016·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Syahir MansorFloris H P van Velden
Aug 15, 2015·Journal of Nuclear Medicine Technology·LisaAnn TrembathMichael D Devous
Jun 9, 2021·Physics in Medicine and Biology·Andre Z Kyme, Roger R Fulton
Sep 30, 2021·MSphere·Zhi ZhangXilin Zhao

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