Methods of Isolation and Characterization of Stem Cells from Different Regions of Oral Cavity Using Markers: A Systematic Review

International Journal of Stem Cells
Kavarthapu AvinashJayakumar Nadathur Dooraiswamy

Abstract

Periodontitis is a destructive inflammatory disorder of the periodontium caused by the destruction of periodontal tissues namely the PDL, cementum, alveolar bone, and gingiva. Once these tissues are lost, the foremost goal of periodontal therapy is to regenerate the diseased tissues if possible to their original form, architecture, and function. Various regenerative procedures were employed and still a gap was found in achieving the goal. As stem cells are characterized by their ability to self-renew and differentiate to produce specialized cells, there could be a possibility of using them for regenerative therapy. Recently, dental tissues such as the PDL, the dental pulp and the tooth follicle have been recognized as readily available sources of adult stem cells. The aim was to identify the various sources and methodologies in isolation of stem cells from human oral cavity and its differentiation into various lineages using markers. The electronic databases PUBMED, GOOGLE SCHOLAR, SCIENCE DIRECT, COCHRANE LIBRARY along with a complimentary manual search of all periodontics journal till the year 2016. Thirteen articles were selected on the basis of the inclusion criteria. Isolation of stem cells from oral cavity through various...Continue Reading

Citations

Apr 14, 2018·Photomedicine and Laser Surgery·Fatima ZaninMarcia Martins Marques
Jul 14, 2017·Computational and Mathematical Methods in Medicine·Nan JiaXiaonan Luo
Oct 12, 2019·International Journal of Molecular Sciences·Oriana TrubianiJacopo Pizzicannella
Jan 18, 2019·Journal of Oral and Maxillofacial Pathology : JOMFP·Shwetha Hulimavu Ramaswamy ReddyG N Ashok
May 30, 2020·Veterinary Ophthalmology·Allison M CleymaetMichala de Linde Henriksen
Feb 9, 2019·Journal, Genetic Engineering & Biotechnology·Dalia FleifelSherif F El-Khamisy

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BETA
flow cytometry

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