Methods of reconstruction after esophagectomy on long-term health-related quality of life: a prospective, randomized study of 5-year follow-up

Medical Oncology
Min ZhangQing-Chen Wu

Abstract

The health-related quality of life (HRQL) is generally accepted as an important parameter for patients undergoing oncologic surgery. We conducted this prospective, randomized study to compare the effect of narrow gastric tube (NGT) reconstruction and whole-stomach (WS) reconstruction on the long-term HRQL in patients after esophagectomy. One hundred and four patients undergoing esophagectomy were enrolled in our study from 2007 to 2008, with 52 in NGT group and 52 in WS group. A questionnaire with reference to the European Organization for Research and Treatment of Cancer QLQ-C30 and QLQ-OES18 was used to assess the HRQL at 3 weeks, 6 months, 1, 2, 3, 4, and 5 years after esophagectomy. Data collection and follow-up were performed regularly. No significant difference was found between NGT group and WS group in the patients' baseline characteristics. Patients in NGT group had decreased risk of postoperative reflux esophagitis by comparison with those in WS group. The 5-year cumulative survival rate was 42 % (NGT) and 27 % (WS), respectively. Compared with WS group, a significant increased survival rate (P = 0.027) was found in NGT group. Additionally, patients had lower dysphagia scores (better) in NGT group than those in WS gro...Continue Reading

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Citations

Nov 4, 2015·Journal of Surgical Oncology·Annelies DeldyckePiet Pattyn
Mar 24, 2016·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·L HaverkampR V Hillegersberg
Nov 20, 2016·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·Piers R BoshierGeorge B Hanna
Aug 15, 2020·The Korean Journal of Thoracic and Cardiovascular Surgery·Jong Ho Cho
Jul 30, 2020·Annals of Gastroenterological Surgery·Kazuhiro YoshidaKazuya Yamaguchi

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