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Methods to study toxic transgenes in C. elegans: an analysis of protease-dead separase in the C. elegans embryo

bioRxiv

Feb 6, 2014

Diana M MitchellJoshua N. Bembenek

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Abstract

We investigated whether the protease activity of separase, which is required for chromosome segregation, is also required for its other roles during anaphase in C. elegans given that non-proteolytic functions of separase have been identified in other organisms. We find that expression o...read more

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  • Methods to study toxic transgenes in C. elegans: an analysis of protease-dead separase in the C. elegans embryo

    bioRxiv

    Feb 6, 2014

    Diana M MitchellJoshua N. Bembenek

    PMID: 990002444

    DOI: 10.1101/002444

    Abstract

    We investigated whether the protease activity of separase, which is required for chromosome segregation, is also required for its other roles during anaphase in C. elegans given that non-proteolytic functions of separase have been identified in other organisms. We find that expression o...read more

    3
    1

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