Methotrexate patient education: a quality improvement study

Arthritis Care and Research : the Official Journal of the Arthritis Health Professions Association
M R BurmaK G Saag

Abstract

To determine patients' knowledge of the safe use and toxicity of methotrexate (MTX) and to define educational interventions implemented by a rheumatology nurse that improved patients' understanding of MTX therapy. One hundred eighty-three patients from a university-based rheumatology clinic who were taking MTX completed an initial knowledge questionnaire concerning the proper use and possible toxicity of MTX. Following completion, a nurse reviewed the correct answers with each patient and provided written information on MTX. One hundred thirty-eight of these patients completed a followup questionnaire at the next visit or by mail. The questionnaires were analyzed, and a total MTX knowledge score was calculated. MTX knowledge improved significantly between questionnaires; mean total score (+/- SD) increased from 7.32 +/- 3.99 to 10.23 +/- 3.29 (P < 0.001). After accounting for a person's initial questionnaire score, the addition of a supplemental "MTX pocket-card" was associated with a higher score on the follow-up questionnaire (adjusted odds ration [OR] = 2.37; 95% confidence interval [CI] 1.14, 4.95; P = 0.021). Patients over age 55 were 4 times more likely to have a poorer score compared with patients under age 45 (adjusted ...Continue Reading

References

Nov 1, 1992·Arthritis and Rheumatism·J N KatzM H Liang
Apr 1, 1991·Seminars in Arthritis and Rheumatism·C J ScullyG W Cannon
May 1, 1989·Cleveland Clinic Journal of Medicine·P L KrallW S Wilke
May 1, 1988·Arthritis and Rheumatism·R J RothenbergA G Finesilver
Jul 1, 1972·Clinical Pharmacology and Therapeutics·R B Stewart, L E Cluff
Jun 1, 1968·The Journal of Pediatrics·A MilunskyM F Gaynor
Jan 1, 1982·Journal of Chronic Diseases·S A Mazzuca
May 12, 1994·The New England Journal of Medicine·J M Cash, J H Klippel
Jun 1, 1993·Baillière's Clinical Rheumatology·L H Daltroy
Nov 6, 1987·Patient Education and Counseling·K LorigV Gonzalez

❮ Previous
Next ❯

Citations

Sep 17, 2010·Pediatric Rheumatology Online Journal·Aarat M PatelPaul Rosen
Nov 4, 2015·Journal of Clinical Nursing·Françoise FayetJean-Jacques Dubost
Sep 11, 2004·Haemophilia : the Official Journal of the World Federation of Hemophilia·D Magli-BariozP Molho
May 16, 2014·Annals of the New York Academy of Sciences·Cécile Gaujoux-Viala, Laure Gossec
Mar 20, 2012·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Evin SowdenLee-Suan Teh

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.