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Methyl-CpG binding domain 2 (Mbd2) is an Epigenetic Regulator of Autism-Risk Genes and Cognition

bioRxiv

Jan 16, 2018

Elad LaxMoshe Szyf

Abstract

The Methyl-CpG-Binding Domain Protein family has been implicated in neurodevelopmental disorders. The Methyl-CpG-binding domain 2 (Mbd2) binds methylated DNA and was shown to play an important role in cancer and immunity. Some evidence linked this protein to neurodevelopment. However, i...read more

Mentioned in this Paper

Hippocampus (Brain)
MBD2 gene
DPEP2 gene
MBD2 protein, human
Mice, Knockout
Autism Spectrum Disorders
Regulation of Binding
Neurodevelopmental Disorders
Emotional Disorder
Biochemical Pathway
4
1
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Methyl-CpG binding domain 2 (Mbd2) is an Epigenetic Regulator of Autism-Risk Genes and Cognition

bioRxiv

Jan 16, 2018

Elad LaxMoshe Szyf

DOI: 10.1101/247197

Abstract

The Methyl-CpG-Binding Domain Protein family has been implicated in neurodevelopmental disorders. The Methyl-CpG-binding domain 2 (Mbd2) binds methylated DNA and was shown to play an important role in cancer and immunity. Some evidence linked this protein to neurodevelopment. However, i...read more

Mentioned in this Paper

Hippocampus (Brain)
MBD2 gene
DPEP2 gene
MBD2 protein, human
Mice, Knockout
Autism Spectrum Disorders
Regulation of Binding
Neurodevelopmental Disorders
Emotional Disorder
Biochemical Pathway
4
1

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