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Methylation-sensitive expression of a DNA demethylase gene serves as an epigenetic rheostat

PLoS Genetics

Mar 1, 2015

Ben P WilliamsMary A Gehring

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Abstract

Genomes must balance active suppression of transposable elements (TEs) with the need to maintain gene expression. In Arabidopsis, euchromatic TEs are targeted by RNA-directed DNA methylation (RdDM). Conversely, active DNA demethylation prevents accumulation of methylation at genes proxi...read more

Mentioned in this Paper

Brassicales
Angiosperms
Gene Expression
DNA Sequence
Reverse Transcriptase Polymerase Chain Reaction
Fertilization
Species
Study of Epigenetics
DNA Transposable Elements
Proximal
29
2
111
Paper Details
References
    • References58
    • Citations12
    • References58
    • Citations12
  • Methylation-sensitive expression of a DNA demethylase gene serves as an epigenetic rheostat

    PLoS Genetics

    Mar 1, 2015

    Ben P WilliamsMary A Gehring

    PMID: 25826366

    DOI: 10.1371/journal.pgen.1005142

    Abstract

    Genomes must balance active suppression of transposable elements (TEs) with the need to maintain gene expression. In Arabidopsis, euchromatic TEs are targeted by RNA-directed DNA methylation (RdDM). Conversely, active DNA demethylation prevents accumulation of methylation at genes proxi...read more

    Mentioned in this Paper

    Brassicales
    Angiosperms
    Gene Expression
    DNA Sequence
    Reverse Transcriptase Polymerase Chain Reaction
    29
    2
    111

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    Paper Details
    References
    • References58
    • Citations12
    • References58
    • Citations12
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