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Methylation-sensitive expression of a DNA demethylase gene serves as an epigenetic rheostat

bioRxiv

Mar 4, 2015

Ben P WilliamsMary A Gehring

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Abstract

Genomes must balance active suppression of transposable elements (TEs) with the need to maintain gene expression. In Arabidopsis, euchromatic TEs are targeted by RNA-directed DNA methylation (RdDM). Conversely, active DNA demethylation prevents accumulation of methylation at genes proxi...read more

Mentioned in this Paper

Gene Expression
DNA, A-Form
Species
Study of Epigenetics
DNA Transposable Elements
Proximal
Parasites
Oxidoreductases, N-Demethylating
Mutant
Arabidopsis
10
1
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  • Methylation-sensitive expression of a DNA demethylase gene serves as an epigenetic rheostat

    bioRxiv

    Mar 4, 2015

    Ben P WilliamsMary A Gehring

    PMID: 990015941

    DOI: 10.1101/015941

    Abstract

    Genomes must balance active suppression of transposable elements (TEs) with the need to maintain gene expression. In Arabidopsis, euchromatic TEs are targeted by RNA-directed DNA methylation (RdDM). Conversely, active DNA demethylation prevents accumulation of methylation at genes proxi...read more

    Mentioned in this Paper

    Gene Expression
    DNA, A-Form
    Species
    Study of Epigenetics
    DNA Transposable Elements
    10
    1

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