Methylisothiazolinone contact allergy in Croatia: Epidemiology and course of disease following patch testing

Contact Dermatitis
Suzana Ljubojević HadžavdićJeanne D Johansen

Abstract

Methylisothiazolinone (MI) caused an epidemic of contact allergy in Europe, as shown by data from many countries, but no studies from Croatia exist. Also, data are lacking on the severity of allergic contact dermatitis (ACD) caused by MI, and its impact on quality of life and prognosis. To determine the frequency of MI contact allergy among Croatian dermatitis patients, identify causative exposures, assess the impact of disease, and study the prognosis. Data were collected for consecutive dermatitis patients with MI contact allergy patch tested in Croatia between November 2, 2015 and November 3, 2016. MI contact allergy was diagnosed in 13.2% of 798 tested patients. The most frequent dermatitis locations were the hands (76%) and face (61%). In 89.3% of patients, MI contact allergy was found to be of current relevance. Considerable severity and impact on daily life of disease was found at the first consultation, but this significantly decreased until follow-up 3 months later. Patch testing is the standard method for the diagnosis of ACD, and it has been shown to have an important beneficial effect on prognosis. The severity of MI ACD and the impact on daily life emphasize the need for prevention.

References

Apr 1, 1994·Contact Dermatitis·F M LewisD J Gawkrodger
Apr 23, 2002·The British Journal of Dermatology·K F ThomsonB Pollock
Nov 26, 2003·Journal of the American Academy of Dermatology·Deana L KadykDonald V Belsito
Jul 16, 2010·Contact Dermatitis·Juan García-GavínAn Goossens
Dec 6, 2012·BMJ : British Medical Journal·Michael Dyrgaard LundovJeanne Duus Johansen
Jun 21, 2013·Contact Dermatitis·John P McFaddenIan R White
Jul 31, 2013·Contact Dermatitis·Wolfgang UterAxel Schnuch
Oct 15, 2013·Contact Dermatitis·Michael D LundovJeanne D Johansen
Mar 5, 2014·Contact Dermatitis·Kaija LammintaustaKatri Suuronen
Mar 19, 2014·Contact Dermatitis·Graham A Johnston, UNKNOWN contributing members of the British Society for Cutaneous Allergy (BSCA)
Mar 19, 2014·Contact Dermatitis·Ana GameiroMargarida Gonçalo
May 30, 2014·Environmental Science & Technology·Michael D LundovJeanne D Johansen
Jan 23, 2016·Regulatory Toxicology and Pharmacology : RTP·UNKNOWN Scientific Committee Of Consumer Safety, A M Giménez-Arnau
Nov 20, 2016·Contact Dermatitis·Elena Garcia-HidalgoKonrad Hungerbühler
Dec 30, 2016·Contact Dermatitis·Jakob F SchwensenUNKNOWN European Environmental Contact Dermatitis Research Group
Apr 8, 2017·Contact Dermatitis·Rachel UrwinMark Wilkinson
Aug 3, 2017·Contact Dermatitis·Anna M AnderssonJeanne D Johansen

❮ Previous
Next ❯

Citations

Jan 31, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·A DusefanteF Larese Filon
May 31, 2019·Current Opinion in Allergy and Clinical Immunology·Jeanne D Johansen, Thomas Werfel
Oct 9, 2019·Contact Dermatitis·K BelharethJ Zili
Aug 17, 2019·Journal of the European Academy of Dermatology and Venereology : JEADV·Wolfgang UterUNKNOWN European Environmental Contact Dermatitis Research Group
Apr 5, 2020·International Journal of Environmental Research and Public Health·Wolfgang UterIan R White
Jul 15, 2021·International Journal of Toxicology·Christina L BurnettBart Heldreth

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.