PMID: 3746182Jun 1, 1986Paper

Methylmercury exposure and mortality in southern Japan: a close look at causes of death

Journal of Epidemiology and Community Health
H TamashiroE S Lee

Abstract

This study examines mortality patterns by cause of death to investigate the effect of exposure to methylmercury in a small area of Minamata City (Kumamoto Prefecture, Japan), which has the highest concentration of patients with Minamata disease. Standardised mortality ratios (SMRs) are computed by cause of death for the study area, using the age specific rates of the entire city as a standard. The SMRs for liver cancer and chronic liver disease in the study area are significantly higher than unity and are consistent with the mortality patterns of registered Minamata disease patients. While an excess mortality is observed for cerebral haemorrhage, mortality from cerebral infarction and other cerebrovascular diseases is considerably lower in the study area. The multiple risk factors of liver related diseases and a possible explanation for the cerebrovascular mortality patterns are discussed to suggest further investigation.

References

Jul 18, 1979·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·A G Shaper
Jan 1, 1984·International Archives of Occupational and Environmental Health·H TamashiroL H Roht
Mar 1, 1981·Journal of Toxicology and Environmental Health·C J TurnerS Yamashiro

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Citations

Mar 16, 2007·International Archives of Occupational and Environmental Health·Takashi YorifujiNorito Kawakami
Mar 1, 1987·Archives of Environmental Health·H TamashiroE S Lee
Jul 21, 2010·International Journal of Environmental Research and Public Health·Ping LiGuangle Qiu
Sep 30, 2008·Journal of Applied Toxicology : JAT·Xiaolei JinRekha Mehta
Oct 1, 2015·Biological Trace Element Research·Hye-Kyung ChungKyung Rae Kim
Mar 13, 2003·The Tohoku Journal of Experimental Medicine·Tomoko OkaMakoto Futatsuka
Dec 1, 1986·Bulletin of Environmental Contamination and Toxicology·H TamashiroM H Smolensky
May 1, 1986·Bulletin of Environmental Contamination and Toxicology·H TamashiroM H Smolensky
Mar 9, 2018·Environmental Monitoring and Assessment·Yury G UdodenkoViktor V Zakonnov
Jan 11, 2017·Environmental Toxicology·Shubhankar DasSatish B S Rao
Jun 21, 2019·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Natalie H MatthewsEunyoung Cho

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