Methylphenidate treatment of patients with head and neck cancer

Head & Neck Surgery
F Fernandez, F Adams

Abstract

Five organically impaired and depressed head and neck cancer patients had a marked therapeutic response to methylphenidate (MPD). There was a rapid remission of depressive and cognitive dysfunctions without adverse side effects. The relationship of cognitive, behavioral, and affective symptoms to brain function is discussed. To rule out treatable cognitive and affective disorders, neurobehavioral assessment of the depressed head and neck cancer patient is stressed, and diagnostic and treatment guidelines are given. The results suggest that further evaluation is warranted of the use of MPD in treating seriously ill cancer patients who have either compromised brain function or depression.

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Citations

Jan 5, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mark RozansMarc J Kahn
Aug 22, 2008·Journal of Palliative Medicine·Dilara Seyidova KhoshknabiGuang H Yue
Dec 7, 2011·The American Journal of Hospice & Palliative Care·Eric Prommer
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Jan 1, 1995·International Journal of Psychiatry in Medicine·G R Brown
Oct 17, 1998·Journal of Psychosomatic Research·D J Newport, C B Nemeroff

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