Methylthioxylose--a jewel in the mycobacterial crown?

Organic & Biomolecular Chemistry
W Bruce Turnbull, Susanne A Stalford

Abstract

Ten years ago an unusual sugar was discovered in a cell wall polysaccharide of Mycobacterium tuberculosis. Structural elucidation revealed the presence of the first thiosugar in a bacterial polysaccharide. Synthetic studies have helped to define its relative and absolute configuration as α-D-methylthioxylofuranosyl. While its biosynthetic origins remain the subject of speculation, work has begun to define its possible biological roles.

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Citations

Jun 11, 2014·Critical Reviews in Biochemistry and Molecular Biology·Shiva Kumar AngalaMary Jackson
Oct 22, 2015·Annual Review of Microbiology·Monika JankuteGurdyal S Besra
Apr 4, 2018·The Journal of Immunology : Official Journal of the American Association of Immunologists·Alok ChoudharyAbraham Pinter
Feb 15, 2018·Nature Chemical Biology·Shiva K AngalaMary Jackson
Jun 4, 2020·The Journal of Organic Chemistry·Bo-Shun Huang, Todd L Lowary
Jun 14, 2018·The Journal of Organic Chemistry·Li ZhangTodd L Lowary

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