MICA∗078: A novel allele identified in a Moroccan individual affected by celiac disease

Human Immunology
Daniela PiancatelliAbdellah Essaid

Abstract

A novel MICA allele, MICA(∗)078, has been identified during HLA/MICA high resolution typing of Moroccan patients with celiac disease. MICA(∗)078 shows an uncommon variation at a highly conserved nucleotide position (nt 493, G → A), resulting in one amino acid change at codon 142 (V → I) of MICA gene (compared to MICA(∗)002:01), located in the α2-domain, in which V142 is the common residue.

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Citations

Nov 26, 2015·Tissue Antigens·Steven G E Marsh

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