PMID: 9552817Feb 1, 1997Paper

Miconazole lacquer in the treatment of denture stomatitis: clinical and microbiological findings in Chinese patients

Clinical Oral Investigations
A P DiasM T Lee

Abstract

To investigate the efficacy of a miconazole lacquer in producing mycological and clinical cure of Candida-associated denture stomatitis in a Chinese cohort and to study the microbiology of the conditions. A cross-sectional study of the clinical and microbiological features of the condition and its response to treatment with the lacquer. Twenty-one Chinese adults with palatal erythema; 15 denture wearers matched for age and sex as controls for microbiology. Clinical examination, impression for culture, photograph of palate to monitor response to treatment, and lacquer application on upper denture base on days 0, 7 and 14. Impression and photograph repeated on day 21; impression cultures quantified by image analysis. Palatal impression in controls; dummy impression as control for impression culture procedures. Severity of lesion, incidence and type of microorganism at presentation and during treatment; qualitative and quantitative assessment of yeast growth; the latter by statistical analysis of pixel units of yeast colonies; correlation of clinical and mycological cure. Out of the 21 lesions (16 Newton's stage I and 5 stage II), 57% had yeasts at presentation, 10% coliforms and 33% no significant growth. Clinical cure in 3 weeks...Continue Reading

Citations

Sep 17, 2015·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Carolina Menezes MacielPaulo Ricardo Saquete Martins-Filho
Jun 28, 2016·Clinics in Dermatology·Jillian W Millsop, Nasim Fazel
Jul 6, 2010·Dermatologic Therapy·Victoria Sharon, Nasim Fazel
Feb 27, 2016·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Mamoru MurakamiMasahiro Nishimura
May 11, 2002·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·A N Ellepola, L P Samaranayake
Sep 12, 2012·European Journal of Applied Physiology·Jacek ZielińskiEwa Słomińska
May 30, 2009·European Journal of Applied Physiology·Jacek ZielińskiMaria Laurentowska

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