Micro-Hotspots of Risk in Urban Cholera Epidemics

The Journal of Infectious Diseases
Andrew S AzmanJustin Lessler

Abstract

Targeted interventions have been delivered to neighbors of cholera cases in major epidemic responses globally despite limited evidence for the impact of such targeting. Using data from urban epidemics in Chad and Democratic Republic of the Congo, we estimate the extent of spatiotemporal zones of increased cholera risk around cases. In both cities, we found zones of increased risk of at least 200 meters during the 5 days immediately after case presentation to a clinic. Risk was highest for those living closest to cases and diminished in time and space similarly across settings. These results provide a rational basis for rapidly delivering targeting interventions.

References

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Citations

May 28, 2020·The American Journal of Tropical Medicine and Hygiene·Francis H NanzalukaJoan Brunkard
Mar 20, 2019·The American Journal of Tropical Medicine and Hygiene·Mellisa RoskoskyDavid A Sack
May 31, 2019·PLoS Neglected Tropical Diseases·Angèle H M BénardAmanda K Debes
Apr 17, 2019·PLoS Neglected Tropical Diseases·Stanislas RebaudetRenaud Piarroux
Oct 24, 2020·The Lancet Infectious Diseases·Ruwan RatnayakeFrancesco Checchi
Sep 23, 2021·The Journal of Infectious Diseases·Andrew S AzmanEmily S Gurley

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