Micro-poromechanics model of fluid-saturated chemically active fibrous media

Zeitschrift für angewandte Mathematik und Mechanik
Anil MisraPaulette Spencer

Abstract

We have developed a micromechanics based model for chemically active saturated fibrous media that incorporates fiber network microstructure, chemical potential driven fluid flow, and micro-poromechanics. The stress-strain relationship of the dry fibrous media is first obtained by considering the fiber behavior. The constitutive relationships applicable to saturated media are then derived in the poromechanics framework using Hill's volume averaging. The advantage of this approach is that the resultant continuum model accounts for the discrete nature of the individual fibers while retaining a form suitable for porous materials. As a result, the model is able to predict the influence of micro-scale phenomena, such as the fiber pre-strain caused by osmotic effects and evolution of fiber network structure with loading, on the overall behavior and in particular, on the poromechanics parameters. Additionally, the model can describe fluid-flow related rate-dependent behavior under confined and unconfined conditions and varying chemical environments. The significance of the approach is demonstrated by simulating unconfined drained monotonic uniaxial compression under different surrounding fluid bath molarity, and fluid-flow related cree...Continue Reading

References

Aug 1, 1991·Journal of Biomechanical Engineering·W M LaiV C Mow
Feb 1, 1980·Journal of Biomechanical Engineering·V C MowC G Armstrong
Mar 27, 1999·Journal of Biomechanics·S C Cowin
Sep 6, 2000·Nature Biotechnology·H PetiteG Guillemin
Oct 19, 2000·Journal of Biomechanical Engineering·P BursaćD Stamenović
Apr 10, 2003·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Michael S Detamore, Kyriacos A Athanasiou
Mar 23, 2004·Nature Materials·Ying Luo, Molly S Shoichet
Feb 25, 2005·Proceedings of the National Academy of Sciences of the United States of America·Boris I Shraiman
May 3, 2005·Journal of Biomechanics·W WilsonR Huiskes
Jul 20, 2006·Journal of the Royal Society, Interface·Anil MisraJ Lawrence Katz
Oct 17, 2008·Journal of Biomechanics·Salvatore Federico, Walter Herzog
Mar 31, 2009·Journal of Dental Research·X L LuX E Guo
Jun 23, 2009·Journal of Biomechanics·Michael S SacksDavid E Schmidt
Jul 3, 2010·Medical Engineering & Physics·K A M KulmalaJ Töyräs
May 3, 2011·Journal of the Mechanics and Physics of Solids·D AmbrosiK Garikipati
Jul 20, 2012·Annual Review of Biomedical Engineering·G A Ateshian, J D Humphrey
Sep 3, 2013·Journal of Polymer Science. Part B, Polymer Physics·Ferenc Horkay
Nov 23, 2013·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·G A Holzapfel, R W Ogden

❮ Previous
Next ❯

Citations

May 17, 2018·Journal of Physics. Condensed Matter : an Institute of Physics Journal·Ranganathan ParthasarathyLizhi Ouyang
Dec 19, 2018·Biointerphases·Ranganathan ParthasarathyPaulette Spencer
May 19, 2019·Biomechanics and Modeling in Mechanobiology·Ivan GiorgioTomasz Lekszycki
Sep 18, 2018·Proceedings. Mathematical, Physical, and Engineering Sciences·I GiorgioE Turco

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.