PMID: 9179470Mar 1, 1997Paper

Microalbuminuria and associated clinical features among Brazilians with insulin dependent diabetes mellitus

Diabetes Research and Clinical Practice
M B GomesH Matos

Abstract

With the objective to determine the frequency of microalbuminuria, macroalbuminuria and the associated clinic and metabolic features among insulin dependent diabetes mellitus (IDDM) Brazilian patients attending at a general University Hospital, a total of 50 outpatients, aged 21.9 +/- 7 years with IDDM duration of 6.8 +/- 5.8 years were studied cross-sectionally. Urinary albumin excretion rate (AER) was determined in timed overnight urine samples. Microalbuminuria was defined when two out of three urine samples had AER ranging 20-200 micrograms/min. Microalbuminuria was present in 12% of our patients. No macroalbuminuric patient was found. Among patients with diabetes duration < or = 5 years (n = 24), 8.3% (n = 2) had microalbuminuria. Retinopathy was strongly associated with microalbuminuria (P = 0.004) although no proliferative retinopathy was noted. No difference was observed concerning FBG and HBAI between normo and microalbuminuria patients. Univariate analysis has revealed no influence of these variables in AER. Systolic blood pressure (sBP) was high in microalbuminuria patients and stepwise multiple regression analysis has shown that it was the only significant independent variable to influence AER. (R = 0.42 r2 = 0.18 P...Continue Reading

References

Apr 1, 1992·Diabetes Care·UNKNOWN Microalbuminuria Collaborative Study Group
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Jan 1, 1992·Archives of Internal Medicine·R KleinS E Moss
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Citations

Jun 14, 2001·Diabetes Research and Clinical Practice·C N CohenM B Gomes
Nov 13, 2001·American Journal of Ophthalmology·L P AielloJ S Wong
Feb 13, 2001·Clinica Chimica Acta; International Journal of Clinical Chemistry·M B Gomes, M F Gonçalves

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