Microalbuminuria in type II diabetes.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
J E Murray

Abstract

To emphasize the prognostic significance of microalbuminuria in patients with type II diabetes and to summarize interventional studies in patients with non-insulin-dependent diabetes mellitus and nephropathy. The definition of microalbuminuria is reviewed, the implications of its presence are discussed, and published trials of medical intervention to treat proteinuria in patients with type II diabetes are outlined. Microalbuminuria--defined as the presence of 30 to 300 mg of protein in a 24-hour urine specimen or a urinary albumin excretion rate of 20 to 200 mg/min--is frequently present in patients with non-insulin-dependent diabetes mellitus. It has been shown to be an independent cardiovascular risk factor as well as a predictor for the eventual development of renal failure. Intervention trials indicate that treatment with "tight" blood glucose control and antihypertensive agents, especially angiotensin-converting enzyme inhibitors, may be beneficial in reversing early proteinuria or at least in preventing the progression to renal failure. The presence of microalbuminuria in patients with type II diabetes mellitus is associated with premature death from cardiovascular disease and the development of renal failure. Thus, aggre...Continue Reading

References

Apr 1, 1992·Kidney International·E M DamsgaardC E Mogensen
May 1, 1990·Diabetic Medicine : a Journal of the British Diabetic Association·P MartinJ A Davies
Dec 28, 1989·The New England Journal of Medicine·B U IhleP S Kincaid-Smith
Nov 1, 1985·Diabetic Medicine : a Journal of the British Diabetic Association·W GatlingR D Hill
Mar 1, 1988·Diabetic Medicine : a Journal of the British Diabetic Association·A Schmitz, M Vaeth
Jul 1, 1987·The Journal of Diabetic Complications·A Kofoed-EnevoldsenT Deckert
Feb 1, 1987·Kidney International·C E Mogensen
Jan 1, 1985·Uremia Investigation·C E MogensenB Feldt-Rasmussen
May 1, 1984·Diabetic Medicine : a Journal of the British Diabetic Association·R J JarrettT J Murrells
Jun 1, 1984·Diabetologia·E R MathiesenT Deckert
Feb 9, 1984·The New England Journal of Medicine·C E Mogensen
Jul 12, 1984·The New England Journal of Medicine·C E Mogensen, C K Christensen
Jul 1, 1994·Journal of Diabetes and Its Complications·B Feldt-RasmussenJ S Jensen
Sep 30, 1993·The New England Journal of Medicine·UNKNOWN Diabetes Control and Complications Trial Research GroupC Siebert
Feb 1, 1993·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·S M HaffnerM P Stern
Apr 1, 1993·Journal of Diabetes and Its Complications·L A BachG Jerums

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Citations

Jan 17, 2012·The Canadian Journal of Cardiology·Jasem AlbarakNadia A Khan
Sep 2, 2011·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·E R GauntP Simmonds
Aug 30, 2006·Journal of Psychosomatic Research·Mohammed T Abou-Saleh
Nov 4, 2015·PloS One·Raffaele Antonelli IncalziGiuseppe Paolisso
Oct 11, 2016·Neurologic Clinics·David S Younger, Joyce Moon-Howard

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