PMID: 8602338Aug 1, 1995Paper

Microbial alterations in supragingival dental plaque in response to a triclosan-containing dentifrice

Oral Microbiology and Immunology
J J ZambonY Bonta

Abstract

A total of 325 subjects were entered into a double-blind, stratified 2-treatment clinical study that examined the effects of a dentifrice containing 0.3% triclosan, 2% Gantrez copolymer and 0.243% sodium fluoride on supragingival dental plaque and gingivitis. A subset of 159 subjects including 72 men and 87 women participated in the microbiological component of this study, which was designed to detect shifts in supragingival bacterial species in response to triclosan. Subjects were divided into two groups: one performed normal oral hygiene with the triclosan/copolymer dentifrice and a control group used a placebo dentifrice without triclosan. At baseline, 3 and 6 months during treatment and at 6, 12, 18 and 24 weeks post-treatment, supragingival dental plaque was collected from the buccal and lingual surfaces of the 4 first molar teeth and assayed for: 1) bacterial morphotypes by phase-contrast microscopy; 2) select bacterial groups and bacterial species by culture; and 3) target periodontal pathogens including Actinobacillus actinomycetemcomitans, Bacteroides forsythus, Porphyromonas gingivalis and Prevotella intermedia by immunofluorescence microscopy. There were few statistically significant differences between treatment gro...Continue Reading

References

May 1, 1978·Journal of Clinical Periodontology·M A Listgarten, L Helldén
Dec 1, 1979·Journal of Clinical Microbiology·C B WalkerS S Socransky
Jul 1, 1991·Journal of Clinical Periodontology·F J van der Ouderaa
Dec 17, 1985·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·D T SawyerM S McDowell
May 1, 1986·Journal of Clinical Periodontology·N W Chilton, J L Fleiss
Aug 1, 1985·European Journal of Clinical Microbiology·U Berger
Nov 1, 1973·Archives of Oral Biology·O G GoldJ Van Houte
Dec 1, 1967·Archives of Oral Biology·H L Ritz
Apr 1, 1982·Journal of Clinical Microbiology·J Slots
May 1, 1993·Journal of Clinical Periodontology·J LindheA R Volpe
Oct 1, 1958·Journal of Bacteriology·M ROGOSAA J BEAMAN
Dec 1, 1963·Acta Odontologica Scandinavica·H LOE, J SILNESS
May 1, 1965·Journal of Periodontology·H LOES B JENSEN
Jul 1, 1962·The Journal of the American Dental Association·G A QUIGLEY, J W HEIN
Jul 1, 1951·Journal of Bacteriology·M ROGOSAR F WISEMAN

❮ Previous
Next ❯

Citations

Dec 11, 2002·Journal of Clinical Periodontology·Prem Sreenivasan, Abdul Gaffar
Aug 8, 2009·British Dental Journal·Anthony BlinkhornG J Seymour
Jun 4, 2014·BMC Oral Health·Violet I HaraszthyJoseph J Zambon
Oct 9, 2012·Letters in Applied Microbiology·P K SreenivasanJ J Zambon
May 15, 2013·Journal of Periodontal Research·M P CullinanG J Seymour
Oct 3, 2006·The Journal of the American Dental Association·Daniel H FineWilliam De Vizio
Aug 22, 2008·Periodontology 2000·Robin M Davies
May 16, 2002·Periodontology 2000·Gregor J PetersilkaThomas F Flemmig
Oct 27, 2017·Journal of Periodontal Research·L PavezP C Smith
Jun 25, 2016·The Journal of Contemporary Dental Practice·Deema Farsi, Anne Tanner

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergy & Infectious Diseases (ASM)

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Antimicrobial Resistance (ASM)

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Allergy & Infectious Diseases

Allergies result from the hyperreactivity of the immune system to some environmental substance and can be life-threatening. Infectious diseases are caused by organisms including bacteria, viruses, fungi and parasites. They can be transmitted different ways, such as person-to-person. Here is the latest research on allergy and infectious diseases.

Antimicrobial Resistance

Antimicrobial resistance poses a significant threat to the continued successful use of antimicrobial agents for the treatment of bacterial infections.

Actinomycosis

Actinomycosis is a rare, chronic, and slowly progressive granulomatous disease caused by filamentous Gram positive anaerobic bacteria from the Actinomycetaceae family (genus Actinomyces). The disease is characterised by the formation of painful abscesses in the mouth, lungs,breast or gastrointestinal tract. Discover the latest research on actinomycosis here.