Microbial contamination of hydrogel contact lenses

Journal of Applied Microbiology
U Gopinathan Holden

Abstract

Bacterial contamination of contact lenses (CLs) may contribute to CL-related corneal infection and inflammation. This study reports CL biota over time during daily and extended wear. Microbial contamination of a 58% water, ionic hydrogel CL and a 38% water, non-ionic hydrogel CL was evaluated in an Australian and an Indian population. Fifty wearers were repeatedly sampled over 18 months. Overnight CL use did not alter the frequency of positive cultures, nor the spectrum of organisms compared with daily CL wear. There were no differences in type and frequency of CL contamination between the CL types. Positive cultures were more frequently recovered from the Indian population compared with the Australian population. Streptococcus spp. and Propionibacterium spp. were more frequently isolated from the Australian population. Fungi and Bacillus spp. were more frequently isolated from the Indian population. Normal CL biota alone cannot explain the increased rate of infection and inflammation in extended wear.

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Citations

Jan 5, 2010·ACS Applied Materials & Interfaces·Paul J BracherGeorge M Whitesides
Feb 20, 2010·Eye & Contact Lens·Loretta B Szczotka-FlynnMahmoud Ghannoum
Sep 30, 2009·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Loretta B Szczotka-FlynnAlfred Rimm
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May 30, 2002·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Mark D P WillcoxBrien A Holden
Jun 26, 2013·Experimental Eye Research·Mark D P Willcox
May 20, 2015·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Yvonne Tzu-Ying WuFiona Stapleton
Jan 15, 2019·Current Eye Research·Jerome Ozkan, Mark D Willcox
Jun 20, 2002·Cornea·Maria Carmen Garcia-SaenzBeatriz Paredes-Garcia
Nov 20, 2015·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Aaron B ZimmermanG Lynn Mitchell
Nov 19, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jerome OzkanBrien A Holden
Nov 20, 2012·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jerome OzkanBrien A Holden
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Nov 12, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Nagaraju KondaMark D P Willcox
Mar 24, 2016·MBio·Hakdong ShinMaria Gloria Dominguez-Bello
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Oct 12, 2010·Eye & Contact Lens·Mark D P WillcoxHua Zhu
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Jan 27, 2010·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Yvonne T WuFiona Stapleton
May 8, 2015·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Jerome OzkanMark D P Willcox
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Dec 26, 2012·Eye & Contact Lens·Mark D P Willcox
Nov 13, 2007·Eye & Contact Lens·Hua ZhuFiona Stapleton
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Mar 30, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Mark WillcoxLyndon Jones
Sep 4, 2021·Materials Science & Engineering. C, Materials for Biological Applications·Peng DongQingshan Shi

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