Microbial glycolipoprotein-capped silver nanoparticles as emerging antibacterial agents against cholera

Microbial Cell Factories
Geeta GahlawatAnirban Roy Choudhury

Abstract

With the increased number of cholera outbreaks and emergence of multidrug resistance in Vibrio cholerae strains it has become necessary for the scientific community to devise and develop novel therapeutic approaches against cholera. Recent studies have indicated plausibility of therapeutic application of metal nano-materials. Among these, silver nanoparticles (AgNPs) have emerged as a potential antimicrobial agent to combat infectious diseases. At present nanoparticles are mostly produced using physical or chemical techniques which are toxic and hazardous. Thus exploitation of microbial systems could be a green eco-friendly approach for the synthesis of nanoparticles having similar or even better antimicrobial activity and biocompatibility. Hence, it would be worth to explore the possibility of utilization of microbial silver nanoparticles and their conjugates as potential novel therapeutic agent against infectious diseases like cholera. The present study attempted utilization of Ochrobactrum rhizosphaerae for the production of AgNPs and focused on investigating their role as antimicrobial agents against cholera. Later the exopolymer, purified from the culture supernatant, was used for the synthesis of spherical shaped AgNPs of...Continue Reading

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Citations

Feb 18, 2018·Journal of Nanobiotechnology·Khwaja Salahuddin SiddiqiRifaqat A K Rao
Jul 17, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Zdenka BedlovičováAneta Salayová
Nov 19, 2018·Bioprocess and Biosystems Engineering·Ji-Yeon YooHong-Joo Son
Jul 1, 2020·Frontiers in Bioengineering and Biotechnology·Yuzhen WangJun Wu
Mar 21, 2017·Journal of Animal Science and Biotechnology·Emily K Hill, Julang Li
Jan 24, 2019·International Journal of Molecular Sciences·Chengzhu LiaoSie Chin Tjong
Jul 28, 2020·Saudi Journal of Biological Sciences·Khawla Ibrahim Alsamhary
Apr 25, 2018·International Journal of Biological Macromolecules·Asma AnsariAfsheen Aman
Jun 16, 2019·International Journal of Biological Macromolecules·Shweta SinghAnirban Roy Choudhury
Feb 9, 2019·Journal of Medicinal Chemistry·Serenella MediciMaria Antonietta Zoroddu

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Methods Mentioned

BETA
transmission
dynamic light scattering
surface plasmon resonance
surface
X-ray

Software Mentioned

Sigma Plot
EzTaxon
MEGA

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