PMID: 15220732Jun 29, 2004Paper

Microbial keratitis following lamellar keratoplasty

Cornea
Namrata SharmaG Satpathy

Abstract

To determine the predisposing factors, etiologic agents, and clinical and visual outcomes in infectious keratitis following lamellar keratoplasty (LK). One hundred thirty-five eyes (135 patients) that had undergone LK were retrospectively analyzed for the occurrence of infectious keratitis following LK. The parameters evaluated were predisposing factors, seasonal variation, indications and type of LK, time interval between LK and infection, site and depth of infection, etiologic organisms, type of treatment, outcome in terms of graft status, secondary surgery, visual acuity, and the donor tissue profile. The incidence of infectious keratitis following LK was 11.11%. The most significant predisposing factor was persistent epithelial defect (3 eyes) and suture abscesses (3 eyes). Most cases occurred between May and August (9/15). Twelve cases developed infection within 2 weeks of surgery (80%). Seven cases (7/15) occurred with onlay grafts, 6 with inlay grafts, and 2 with large-diameter LK. Cultures of corneal scrapings were positive in 11 eyes (73.3%), and the most common isolated organism was coagulase-negative Staphylococcus (CNS). Only 2 eyes responded to medical therapy, and graft sloughing occurred in 9 cases. Six eyes unde...Continue Reading

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Citations

Aug 26, 2006·Cell and Tissue Banking·Ted Eastlund
Jul 25, 2012·Indian Journal of Ophthalmology·Mohammad Reza Sedaghat, Setareh Sagheb Hosseinpoor
Apr 1, 2011·Eye & Contact Lens·Namrata SharmaJeewan S Titiyal
May 1, 2012·Survey of Ophthalmology·Douglas A LyallFiona Roberts
Mar 27, 2010·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Bhavna ChawlaGita Satpathy
Jan 11, 2007·Survey of Ophthalmology·Rasik B VajpayeeArun Singhvi
Apr 8, 2016·Current Opinion in Ophthalmology·Jose R Davila, Shahzad I Mian
Nov 21, 2020·Survey of Ophthalmology·Namrata SharmaAnthony Aldave
May 5, 2021·The British Journal of Ophthalmology·Shilpa DasSujata Das

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