Microbial production of 1,3-propanediol from glycerol by Klebsiella pneumoniae under micro-aerobic conditions up to a pilot scale

Biotechnology Letters
Hai-Jun LiuZhilong Xiu

Abstract

1,3-Propanediol (1,3-PD) can be produced from glycerol by Klebsiella pneumoniae under micro-aerobic conditions. Recently, this fed-batch fermentation process has been successfully scaled up to 1 m(3). The final 1,3-PD concentration, molar yield and volumetric productivity of 72 g l(-1), 57% and 2.1 g l(-1 )h(-1), respectively, are close to those of 75 g l(-1), 61%, and 2.2 g l(-1 )h(-1) under anaerobic conditions. This process would be suitable for the production of 1,3-PD on a large scale.

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Citations

Mar 6, 2008·Applied Microbiology and Biotechnology·Zhi-Long Xiu, An-Ping Zeng
Oct 6, 2011·Applied Microbiology and Biotechnology·Erik WilkensKlaus-Dieter Vorlop
Jul 19, 2011·Bioprocess and Biosystems Engineering·Kaloyan Petrov, Anton Stoyanov
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Apr 2, 2013·Applied and Environmental Microbiology·Daniel HeinrichAlexander Steinbüchel
Jan 14, 2009·Applied and Environmental Microbiology·Xueming TangWei Shen
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Jul 31, 2013·Bioprocess and Biosystems Engineering·Fatma Gizem AvciNuri Azbar
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