Microbial Roles in Dissolved Organic Matter Transformation in Full-Scale Wastewater Treatment Processes Revealed by Reactomics and Comparative Genomics.

Environmental Science & Technology
Liye WangJinju Geng

Abstract

Understanding the degradation of dissolved organic matter (DOM) is vital for optimizing DOM control. However, the microbe-mediated DOM transformation during wastewater treatment remains poorly characterized. Here, microbes and DOM along full-scale biotreatment processes were simultaneously characterized using comparative genomics and high-resolution mass spectrometry-based reactomics. Biotreatments significantly increased DOM's aromaticity and unsaturation due to the overproduced lignin and polyphenol analogs. DOM was diversified by over five times in richness, with thousands of nitrogenous and sulfur-containing compounds generated through microbe-mediated oxidoreduction, functional group transfer, and C-N and C-S bond formation. Network analysis demonstrated microbial division of labor in DOM transformation. However, their roles were determined by their functional traits rather than taxa. Specifically, network and module hubs exhibited rapid growth potentials and broad substrate affinities but were deficient in xenobiotics-metabolism-associated genes. They were mainly correlated to liable DOM consumption and its transformation to recalcitrant compounds. In contrast, connectors and peripherals were potential degraders of recalc...Continue Reading

References

Feb 25, 2005·Nature·Roger Guimerà, Luís A Nunes Amaral
May 26, 2006·Proceedings of the National Academy of Sciences of the United States of America·M E J Newman
Jun 1, 2012·BMC Bioinformatics·Ye DengJizhong Zhou
Feb 7, 2014·Systematic Biology·Lam si Tung Ho, Cécile Ané
Apr 4, 2014·Bioinformatics·Anthony M BolgerBjoern Usadel
May 3, 2014·Nature Communications·Anne M KellermanLars J Tranvik
Sep 15, 2014·Nature Methods·Johannes AlnebergChristopher Quince
Aug 12, 2015·The ISME Journal·Aaron M SaundersPer H Nielsen
Oct 18, 2015·Nucleic Acids Research·Minoru KanehisaMao Tanabe
Nov 14, 2015·Rapid Communications in Mass Spectrometry : RCM·Juliana D'AndrilliAlan G Marshall
Oct 25, 2016·Nature Communications·Karthik AnantharamanJillian F Banfield
Oct 30, 2016·Science·Kerstin B KsionzekBoris P Koch
Dec 20, 2017·Nature Genetics·Asaf LevyJeffery L Dangl
Jun 26, 2018·Frontiers in Microbiology·Xiaoqin WuRomy Chakraborty
Sep 17, 2018·Microbiome·Gherman V UritskiyJames Taylor
Jan 22, 2019·Analytica Chimica Acta·Miao YuJanusz Pawliszyn
Mar 7, 2019·Frontiers in Microbiology·Beatriz E Noriega-OrtegaJutta Niggemann
Nov 16, 2019·Bioinformatics·Pierre-Alain ChaumeilDonovan H Parks
Nov 20, 2019·Proceedings of the National Academy of Sciences of the United States of America·Andrew J TanentzapThorsten Dittmar
Jun 10, 2020·Nature Microbiology·Alison E MurrayAnna-Louise Reysenbach
Jul 11, 2020·The ISME Journal·Maria Vila-CostaJordi Dachs

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