PMID: 814099Jan 1, 1976

Microbial synergy in experimental intra-abdominal abscess

Infection and Immunity
A B OnderdonkS L Gorbach

Abstract

Intra-abdominal sepsis was studied in Wistar rats by using four microbial species: Escherichia coli, enterococci, Bacteroides fragilis, and Fusobacterium varium. These organisms were implanted into the peritoneal cavity singly and in all possible dual combinations. Results were evaluated by mortality rates and the incidence of intra-abdominal abscesses on autopsy following sacrifice after 7 days. Mortality was restricted to recipients of E. coli, thus implicating coliforms in the acute lethality associated with this experimental model. Intra-abdominal abscesses were produced in 61 of 95 (94%) animals that received the combination of an anaerobe and a facultative organism. Abscesses failed to form with any single strain or with E. coli plus enterococci, and they were detected in one 1 of 19 animals receiving B. fragilis plus F. varium. These results suggest that intra-abdominal abscess formation is related to synergy between anaerobes and facultative bacteria.

Citations

Nov 1, 1977·Journal of Neurosurgery·W W OrrisonV Ramgopal
Jul 27, 1989·The New England Journal of Medicine·B Styrt, S L Gorbach
Jun 1, 1986·Pediatric Annals·L M Dunkle
Feb 15, 1993·Postgraduate Medicine·R K Vemuri, M J Zervos
Mar 1, 1997·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·D A WandallJ H Wandall
Mar 18, 2000·Journal of Chemotherapy·P S Barie
Jan 7, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·W M Kalka-MollD L Kasper
Mar 4, 2000·The Journal of Biological Chemistry·A O TzianabosD L Kasper
Jul 27, 2001·Proceedings of the National Academy of Sciences of the United States of America·A O TzianabosJ C Lee
Mar 1, 1985·New Zealand Veterinary Journal·S S Dobbinson, G W Tannock
Dec 20, 2007·Critical Care Medicine·Robert L ConhaimBruce A Harms
Feb 20, 2009·Surgical Infections·Matthew C Byrnes, John E Mazuski
Jun 29, 2016·Langenbeck's Archives of Surgery·D E Fry
Sep 1, 1989·British Journal of Urology·M D WolachR W deVere White
Feb 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C Chenoweth, D Schaberg
Mar 1, 1990·World Journal of Surgery·T Hau
Jan 1, 1984·Antonie van Leeuwenhoek·D M MacLarenJ A Kaan
Jan 1, 1992·Microbiology and Immunology·R JotwaniK Ueno
Aug 1, 1993·Oral Microbiology and Immunology·M WikströmGunnar Dahlén
Feb 1, 1983·European Journal of Clinical Microbiology·J C HagenT Hashimoto
Feb 22, 2003·Surgical Infections·D E Fry, C R Schermer
Feb 22, 2003·Surgical Infections·D E Fry
May 13, 2006·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Zoltán PéterfiBéla Kocsis
Sep 16, 2003·Critical Care Medicine·John C Marshall, Marilyn Innes
Feb 22, 2011·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Robert L ConhaimBruce A Harms
Oct 7, 2011·World Journal of Surgery·Herman Anthony CarneiroEleftherios Mylonakis
Jan 19, 2012·Nutrients·Asa Hakansson, Goran Molin
Aug 12, 2020·Veterinary Surgery : VS·Rachel W WilliamsDavid E Holt
Oct 31, 1998·Infection·E H Farthmann, U Schöffel
Nov 1, 1984·Diseases of the Colon and Rectum·R W MeijerJ Oldhoff
Dec 1, 1982·European Journal of Clinical Microbiology·J C HagenT Hashimoto
May 1, 1990·The British Journal of Surgery·R SaadiaK D Boffard
Jul 15, 1982·Klinische Wochenschrift·A von Graevenitz
Jan 1, 1986·Scandinavian Journal of Gastroenterology. Supplement·S D Adeyemi, I Ahmed
Dec 3, 1999·The British Journal of Surgery·K BosschaC van der Werken
Jan 1, 1996·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·T NakataniK Kobayashi
Feb 18, 2009·Intensive Care Medicine·Masja LeendertseTom van der Poll
Jul 10, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J-H LeeH-S Lee
Dec 31, 2015·Nature Reviews. Microbiology·Apollo StacyMarvin Whiteley
Jul 17, 2014·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·K JindaiN Safdar
Mar 5, 2020·MBio·Anushila ChatterjeeBreck A Duerkop
Jun 27, 2020·Frontiers in Psychiatry·Zahra Amirkhanzadeh BarandouziXiaomei S Cong
Mar 1, 1990·The British Journal of Surgery·D Kingston, D V Seal
Mar 1, 1988·The British Journal of Surgery·J DavsonL Turner
Jan 22, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Francesca StingeleA O Tzianabos
Dec 1, 1992·The Journal of Laryngology and Otology·C E deSouzaG H Tilve
Dec 14, 1990·Pharmaceutisch Weekblad. Scientific Edition·F M KauerW L Manson
Sep 19, 2003·Current Infectious Disease Reports·Peter Linden
Nov 15, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·P SeguinY Malledant
Feb 1, 1990·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C M Lewis, M J Zervos
Jan 30, 2007·Expert Opinion on Pharmacotherapy·Ioannis P KioumisDavid P Nicolau
Sep 1, 1979·The Journal of Urology·R B JonesJ A Tremann
Dec 31, 2019·Mediators of Inflammation·Federica MurandoLorenzo Cobianchi
Jun 22, 1999·Infection and Immunity·L E ComstockD L Kasper

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Abdomen
Abscess
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