PMID: 16508207Mar 2, 2006Paper

Microbiological contamination of laboratory mice and rats in Korea from 1999 to 2003

Experimental Animals
Young-Suk WonYang-Kyu Choi

Abstract

To survey the microbiological contamination of laboratory mice and rats in Korea during a 5-year period, we monitored animals housed in mouse and rat facilities with either barrier or conventional systems. At barrier and conventional mouse facilities, the most important pathogen identified was mouse hepatitis virus (MHV), while Mycoplasma pulmonis was the most important pathogen at conventional rat facilities. Interestingly, hantavirus was recovered from both barrier and conventional mouse facilities. The most common protozoon identified was Tritrichomonas muris in mouse facilities and Entamoeba muris in rat facilities. In addition, we found that the microbiological contamination of mice and rats in conventional facilities was severe. These results suggest that conventional facilities should be renovated and monitored regularly to decrease microbiological contamination. We also propose that hantavirus should be monitored in Korea as an important mouse pathogen.

References

Nov 1, 1989·The Journal of General Virology·M TamuraK Yamanishi
Oct 1, 1985·Journal of Medical Virology·K T McKeeC J Peters
Dec 1, 1988·The Journal of General Virology·L J BaekD C Gajdusek
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Citations

Sep 26, 2013·The Journal of Veterinary Medical Science·Atsushi AsanoTakashi Agui
Apr 27, 2007·Experimental Animals·Young-Suk WonYang-Kyu Choi
Jul 2, 2015·The Journal of Eukaryotic Microbiology·Alison S JacobC Graham Clark
Jul 15, 2015·PloS One·Shrruthi ManjunathRamachandra S Gudde
Nov 19, 2008·Laboratory Animals·Kathleen R Pritchett-CorningCharles B Clifford
Feb 6, 2014·Laboratory Animals·UNKNOWN FELASA working group on revision of guidelines for health monitoring of rodents and rabbitsM Raspa

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