PMID: 9440778Jan 24, 1998Paper

Microbiology of nosocomial sinusitis in mechanically ventilated children

Archives of Otolaryngology--head & Neck Surgery
Itzhak Brook

Abstract

To assess the bacteriology of nosocomial sinusitis in mechanically ventilated children. Retrospective review of sinus aspirate specimens obtained from 20 children with nosocomial sinusitis. The specimens were processed for aerobic and anaerobic bacteria. A total of 58 isolates (2.9 per specimen), 30 aerobic or facultative (1.5 per specimen) and 28 anaerobic (1.4 per specimen), were recovered. Aerobes only were present in 8 patients (40%), anaerobes only in 5 (25%), and mixed aerobic and anaerobic flora in 7 (35%). The predominant aerobes were Pseudomonas aeruginosa (6 isolates), Staphylococcus aureus (5 isolates), Escherichia coli (3 isolates), and Klebsiella pneumoniae (3 isolates). The predominant anaerobes were Peptostreptococcus species (8 isolates), Prevotella species (6 isolates), and Fusobacterium species (4 isolates). Forty-one beta-lactamase bacteria were recovered from 14 specimens (70%). Thirty isolates similar to the sinus isolates were also recovered from the trachea, 6 from blood culture specimens, and 6 from other sites. Anaerobes were more commonly isolated from sinus aspirate samples obtained after 18 days of mechanical ventilation (21 vs 7, P<.05 by chi2). This study demonstrates the polymicrobial aerobic-anae...Continue Reading

Citations

Oct 3, 2013·PLoS Neglected Tropical Diseases·Antoine HuygheUNKNOWN Geneva Study Group on Noma
Nov 30, 2000·Current Infectious Disease Reports·C F Decker
May 10, 2005·Immunology and Allergy Clinics of North America·Michael Zacharisen, Ryan Casper
Mar 6, 2010·Expert Opinion on Pharmacotherapy·Itzhak Brook
Jun 15, 2007·Infectious Disease Clinics of North America·Itzhak Brook
Jan 21, 2009·Periodontology 2000·Itzhak Brook
Apr 6, 2004·Otolaryngologic Clinics of North America·Itzhak Brook
Sep 20, 2016·International Forum of Allergy & Rhinology·Ravi JainRichard Douglas
Feb 24, 2001·The Annals of Otology, Rhinology, and Laryngology·I Brook, E H Frazier
Apr 27, 2000·Current Opinion in Pulmonary Medicine·N S Jones
Dec 18, 2014·The American Journal of Case Reports·Khetam HusseinAyelet Raz-Pasteur

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