Microcanalization in the epididymis to overcome ductal obstruction caused by chronic exposure to chromium - a study in the mature bonnet monkey (Macaca radiata Geoffroy)

Reproduction : the Official Journal of the Society for the Study of Fertility
M Michael AruldhasMohammad Abdulkader Akbarsha

Abstract

In order to apprehend the toxic effects of chromium, an occupational/environmental pollutant, on the epididymis, adult bonnet monkeys were exposed to chromium (VI) in their drinking water at concentrations of 100, 200 and 400 p.p.m. for a chronic period of 180 days. At the end of the experimental period, testicles and segments of epididymis from control and treated monkeys were subjected to light microscopic (resin-embedded semi-thin sections) and transmission electron microscopic analyses. Among the various changes undergone by the epididymal epithelium, the present paper describes the origin of two different kinds of microcanals, probably caused by ductal obstruction. The first type of microcanal, which appears to provide passage for spermatozoa to bypass the obstructed main duct, is comparable with the one already reported in carbendazim-treated efferent ductules of the rat. The second type of microcanal, which is novel, consisted of a lumen in the epithelium enclosed by four to five cells, which are either modified basal cells, principal cells or a hitherto unknown cell type. This novel type of microcanal is suggested to be a device to entrap the spermatozoa which reach the core of the epithelium and may be a mechanism to p...Continue Reading

References

Sep 1, 1979·Fertility and Sterility·N J Alexander, D J Anderson
Jan 1, 1991·Reproductive Toxicology·R C MurthyS V Chandra
Jan 1, 1990·Reproductive Toxicology·D K SaxenaS V Chandra
Feb 1, 1990·International Journal of Andrology·D NashanE Nieschlag
Mar 1, 1990·Mutation Research·S De FloraP Zanacchi
Mar 1, 1989·Journal of Andrology·M J FreundN Oliveira
Aug 1, 1987·Urology·B CruickshankM Barkin
Mar 1, 1984·Journal of Reproduction and Fertility·R Y Ball, M J Mitchinson
Jan 1, 1982·The Journal of Endocrinology·E A Zylber-HaranI M Spitz
Jan 1, 1995·Microscopy Research and Technique·C J FlickingerJ C Herr
Jan 1, 1994·Acta Anatomica·H O GoyalM A Maloney
Aug 1, 1993·International Journal of Andrology·T G Cooper
Jan 1, 1993·Reviews of Environmental Contamination and Toxicology·P M Outridge, A M Scheuhammer
May 1, 1996·Toxicology and Industrial Health·L E Gray, W R Kelce
Jan 1, 1997·Toxicologic Pathology·P C Mann
Apr 16, 1998·Reproductive Toxicology·N H HjollundJ Olsen
Jun 26, 1999·Journal of Toxicology. Clinical Toxicology·D G Barceloux
May 8, 2000·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·J S McGinnS W McDonald
Jun 30, 2000·International Review of Cytology·S W McDonald
Sep 26, 2001·Reproduction : the Official Journal of the Society for the Study of Fertility·V F Agnes, M A Akbarsha
Mar 27, 2002·Reproduction : the Official Journal of the Society for the Study of Fertility·C Holschbach, T G Cooper

❮ Previous
Next ❯

Citations

May 8, 2013·Toxicological Sciences : an Official Journal of the Society of Toxicology·Jiali CaiZhenghong Zuo
Sep 1, 2007·Environmental Toxicology and Pharmacology·Amar K ChandraMahitosh Sarkar
Jun 10, 2008·Anatomia, histologia, embryologia·T A AireM-C Madekurozwa
May 9, 2006·Toxicology and Applied Pharmacology·Senthivinayagam SubramanianMariajoseph Michael Aruldhas
Sep 24, 2015·Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews·Sandhya Mishra, Ram Naresh Bharagava
Apr 2, 2015·Chemosphere·Ana F FerreiraArmindo dos Santos Rodrigues
Apr 26, 2018·Reproduction : the Official Journal of the Society for the Study of Fertility·Cheryl S RosenfeldRex A Hess

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.