Microcomputed Tomography Calibration Using Polymers and Minerals for Enamel Mineral Content Quantitation

Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre
Asma AlyahyaMichael Swain

Abstract

The aim of this paper was to develop calibration standards (CSs) that are readily available for clinical researchers for the quantitation of enamel mineral content. Polyethylene terephthalate (PET), acetal, polyphenylene sulfide (PPS), selenite, Egyptian alabaster, aragonite, and fluorite were fashioned into discs, and their densities were measured and stacked for microcomputed tomography examination. Frame averaging, flat-field correction, pre-filtration, and beam-hardening correction were applied. CSs were checked for homogeneity. The linear relationship between the mean greyscale value (GSV) of each disc and its physically calculated density was explored, and reproducibility was tested. A calibration function was established and then validated using a bovine enamel disc and sound enamel of extracted human premolar teeth. Measured densities were PET (ρ = 1.38 g/cm3), acetal (ρ = 1.41 g/cm3), PPS (ρ = 1.64 g/cm3), selenite (ρ = 2.24 g/cm3), Egyptian alabaster (ρ = 2.7 g/cm3), aragonite (ρ = 2.72 g/cm3), and fluorite (ρ = 3.11 g/cm3). Examination of the profile sections of CSs confirmed the uniformity of GSVs with minimal beam-hardening effect. A squared Pearson correlation coefficient of R2 = 0.994 was determined between the m...Continue Reading

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Citations

Feb 28, 2019·Proceedings of the National Academy of Sciences of the United States of America·Virginia SpanoudakiDaniel G Anderson
Dec 15, 2020·Experimental Eye Research·Sergey Y TkachevMarina S Tkacheva
Mar 30, 2021·JBMR Plus·Michael B ChavezBrian L Foster

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