PMID: 26328323Sep 4, 2015Paper

MicroCT Analysis of Micro-Nano Titanium Implant Surface on the Osseointegration

Journal of Nanoscience and Nanotechnology
Jaesam BanKwidug Yunl

Abstract

This study was to investigate the effects of micro-nano titanium implant surface on the osseointegration. A total of 36 screw-shaped implants were used. The implant surfaces were classified into 3 groups (n = 12): machined surface (M group), nanosurface which is nanotube formation on the machined surface (MA group) and nano-micro surface which is nanotube formation on the RBM surface (RA group). Anodic oxidation was performed at a 20 V for 10 min with 1 M H3PO4 and 1.5 wt% HF solutions. The implants were installed on the humerus on 6 beagles. After 4 and 12 weeks, the morphometric analysis with micro CT (skyscan 1172, SKYSCAN, Antwerpen, Belgium) was done. The data were statistically analyzed with two-way ANOVA. Bone mineral density and bone volume were significantly increased depending on time. RA group showed the highest bone mineral density and bone volume at 4 weeks and 12 weeks significantly. It indicated that nano-micro titanium implant surface showed faster and more mature osseointegration.

Citations

Feb 13, 2019·Journal of Materials Science. Materials in Medicine·Aranka IleaRéka Barabás
Nov 7, 2019·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Erin A BakerCraig R Friedrich

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