Microdissection of Human Esophagogastric Junction Wall with Phase-contrast X-ray CT Imaging

Scientific Reports
Jianfa ZhangMin Su

Abstract

Phase-contrast x-ray imaging using an x-ray interferometer has great potential to reveal the structures inside soft tissues, because the sensitivity of this method to hydrogen, carbon, nitrogen, and oxygen is about 1000 times higher than that of the absorption-contrast x-ray method. In this study, we used phase-contrast X-ray CT to investigate human resected esophagogastric junction. This technology revealed the three-layer structure of the esophagogastric junction wall-mucous, submucosa and muscular layers. The mucous and muscular layers were clearly separated by a loose submucosa layer with a honeycomb appearance. The shape of the mucous and muscular layers was intact. The boundary between the mucous and submucosa layers was distinct, as was the border of the muscular and submucosa layers. The surface of the esophagogastric junction was displayed clearly through 3D reconstruction. The technology might be helpful in the diagnosis of esophagogastric junction lesion, especially for the early adenocarcinoma.

References

Aug 1, 1995·Gastroenterology·R K MittalJ Dent
Mar 27, 1997·The New England Journal of Medicine·R K Mittal, D H Balaban
Jun 14, 2000·AJR. American Journal of Roentgenology·K M SohnK M Kim
Oct 26, 2005·AJR. American Journal of Roentgenology·Kensaku ShimizuYasuhiko Kawakami
May 24, 2006·World Journal of Gastroenterology : WJG·Barry P McMahonHans Gregersen
Apr 26, 2007·World Journal of Gastroenterology : WJG·Barry P McMahonHans Gregersen
Sep 25, 2007·International Journal of Radiation Oncology, Biology, Physics·Ylanga G van der GeldFrank J Lagerwaard
Sep 6, 2011·The Open Medical Informatics Journal·Lu Zhang, Shuqian Luo
Apr 20, 2012·Journal of Synchrotron Radiation·Lei TangXiao-Peng Zhang
Jan 26, 2013·PloS One·Torben Haugaard JensenFranz Pfeiffer
May 11, 2013·Journal of Pediatric Urology·Swarnendu MandalDivakar Dalela
Jun 14, 2013·Biomedical Engineering Online·Philip W MewesHelmut Messmann
Jul 31, 2013·Scientific Reports·Rongbiao TangKe-Min Chen
Aug 21, 2013·International Journal of Radiation Oncology, Biology, Physics·Nan-Jie GongQueenie Chan
Jun 19, 2014·Scientific Reports·Jianfa ZhangMin Su
Jul 26, 2014·Biomedical Engineering Online·Qiang Tao, Shuqian Luo

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Methods Mentioned

BETA
imaging techniques
X-ray
imaging technique
light microscopy

Software Mentioned

Amira
TRACT

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