Microdochectomy for single-duct pathologic nipple discharge and normal or benign imaging and cytology

The Breast : Official Journal of the European Society of Mastology
Sophocles LanitisDimitri J Hadjiminas

Abstract

This study evaluates microdochectomy as a means for diagnosis and treatment of patients with pathological nipple discharge (PND) but with benign or normal imaging and cytology. From 1999 until 2006, in St. Mary's Hospital, 76 patients with the aforementioned condition underwent microdochectomy because of the presence of epithelial cells on nipple smear or for symptomatic relief. Most of the patients had intraductal papillomas (48.7%), duct ectasia (15.8%) or a combination of the two (13.2%). Other benign causes occurred in 11.8% of the patients. Eight patients, including one who was operated for symptomatic relief, had cancer. Of those patients with benign condition, 98% had symptomatic relief while PND recurred twice in one patient. Pre-operative workup and imaging may not be suspicious in patients with single-duct PND and underlying malignancy, therefore, microdochectomy should be considered in such cases.

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Citations

May 12, 2010·Archives of Gynecology and Obstetrics·Josip FajdićChristian Schem
Jan 7, 2010·Women's Health·Stefanos ZervoudisIordanis Navrozoglou
Jan 23, 2016·The Breast Journal·Justin E R E Wong ChungLuc J A Strobbe
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Jul 29, 2019·Breast Cancer Research and Treatment·Konstantinos ZacharioudakisDimitri J Hadjiminas
Oct 21, 2020·Clinical Radiology·D LyonsM C Mahoney

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