PMID: 8948355Oct 1, 1996Paper

Microdosimetric evaluation of relative biological effectiveness for 103Pd, 125I, 241Am, and 192Ir brachytherapy sources

International Journal of Radiation Oncology, Biology, Physics
C S WuuH I Amols

Abstract

To determine the microdosimetric-derived relative biological effectiveness (RBE) of 103Pd, 125I, 241Am, and 192Ir brachytherapy sources at low doses and/or low dose rates. The Theory of Dual Radiation Action can be used to predict expected RBE values based on the spatial distribution of energy deposition at microscopic levels from these sources. Single-event lineal energy spectra for these isotopes have been obtained both experimentally and theoretically. A grid-defined wall-less proportional counter was used to measure the lineal energy distributions. Unlike conventional Rossi proportional counters, the counter used in these measurements has a conducting nylon fiber as the central collecting anode and has no metal parts. Thus, the Z-dependence of the photoelectric effect is eliminated as a source of measurement error. Single-event spectra for these brachytherapy sources have been also calculated by: (a) the Monte Carlo code MCNP to generate the electron slowing down spectrum, (b) transport of monoenergetic electron tracks, event by event, with our Monte Carlo code DELTA, (c) using the concept of associated volume to obtain the lineal energy distribution f(y) for each monoenergetic electron, and (d) obtaining the composite line...Continue Reading

References

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Citations

Nov 19, 1997·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·K HaustermansE van der Schueren
Jan 5, 2002·International Journal of Radiation Oncology, Biology, Physics·David J BrennerElwood P Armour
Apr 17, 2002·International Journal of Radiation Oncology, Biology, Physics·Roger G Dale, Bleddyn Jones
Jan 30, 2009·Journal of Experimental & Clinical Cancer Research : CR·Hong-Qing ZhuangYong Zhao
Jul 5, 2012·Medical Physics·S M OliveiraL Fernandes
Mar 29, 2001·Cardiovascular Radiation Medicine·H I Amols
Mar 29, 2001·Cardiovascular Radiation Medicine·H I Amols
Aug 23, 2005·International Journal of Radiation Oncology, Biology, Physics·Shirley LehnertFrank Verhaegen
Jan 2, 2004·Physics in Medicine and Biology·Christopher N Culbertson, Tatjana Jevremovic
Feb 9, 2007·Radiation Protection Dosimetry·B Reniers, F Verhaegen
Jun 6, 2019·Radiation Protection Dosimetry·Arghya ChattarajD Datta
Jan 15, 2020·Physics in Medicine and Biology·Stefanos MargisDimitris Emfietzoglou
Apr 8, 2020·Radiation Protection Dosimetry·Arghya Chattaraj, T Palani Selvam
Nov 27, 2008·Physics in Medicine and Biology·Brigitte ReniersFrank Verhaegen
Aug 30, 2014·Physics in Medicine and Biology·Fernanda VillegasAnders Ahnesjö
Apr 18, 2002·Journal of Applied Clinical Medical Physics·Timothy D SolbergRobert E Wallace
Mar 13, 2003·Physics in Medicine and Biology·P E LindsayJ J Battista
Mar 7, 2020·Japanese Journal of Clinical Oncology·Jun Itami
Mar 10, 1999·Physics in Medicine and Biology·D J BrennerR E Shefer
Jan 14, 2021·Biomedical Physics & Engineering Express·Humza NusratArman Sarfehnia
Mar 7, 2021·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Ioanna KyriakouDimitris Emfietzoglou
Aug 13, 2021·Physics in Medicine and Biology·Joseph M DeCunhaShirin A Enger

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