Microenvironment of liver regeneration in liver cancer

Chinese Journal of Integrative Medicine
Han-Min Li, Zhi-Hua Ye

Abstract

The occurrence and development of liver cancer are essentially the most serious outcomes of uncontrolled liver regeneration. The progression of liver cancer is inevitably related to the abnormal microenvironment of liver regeneration. The deterioration observed in the microenvironment of liver regeneration is a necessary condition for the occurrence, development and metastasis of cancer. Therefore, the use of a technique to prevent and treat liver cancer via changes in the microenvironment of liver regeneration is a novel strategy. This strategy would be an effective way to delay, prevent or even reverse cancer occurrence, development and metastasis through an improvement in the liver regeneration microenvironment along with the integrated regulation of multiple components, targets, levels, channels and time sequences. In addition, the treatment of "tonifying Shen (Kidney) to regulate liver regeneration and repair by affecting stem cells and their microenvironment" can regulate "the dynamic imbalance between the normal liver regeneration and the abnormal liver regeneration"; this would improve the microenvironment of liver regeneration, which is also a mechanism by which liver cancer may be prevented or treated.

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Citations

May 19, 2020·BioMed Research International·Pengfei SunZhongchao Li
Nov 2, 2020·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Dafeng XuJinfang Zheng
Dec 16, 2020·Animals : an Open Access Journal From MDPI·Abdelaziz GhanemiJonny St-Amand

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