Microfabricated ionic liquid column for separations in dry air

Journal of Chromatography. a
Maxwell Wei-Hao LiXudong Fan

Abstract

Micro gas chromatography (µGC) is a technique developed for rapid, in situ analysis of volatile organic compounds (VOCs) for environmental protection, industrial monitoring, and toxicology. While reduced µGC size and power requirements allow for increased portability, the low moisture and oxygen resilience of current microcolumn technology result in increased peak broadening and tailing for humid samples, which necessitates the use of bulky helium or nitrogen carrier gas cartridges. Developing a microcolumn to address these deficiencies is desirable to improve µGC field performance and further reduce µGC system size. This paper reports the development and characterization of a microfabricated phosphonium ionic liquid (µIL) column and demonstrates separation of both polar and nonpolar compounds using this column via analyses of alcohols, chloroalkanes, aromatics, aldehydes, fatty acid methyl esters, and alkanes. The µIL column achieved operation at temperatures up to 345 °C for fatty acid methyl ester and alkane separation. Notably, all separations in this study used dry air as the carrier gas, showing that analysis of a diverse range of compounds was possible in the presence of oxygen. After exposure to dry air for 48 h at temp...Continue Reading

References

May 1, 2004·Analytical Chemistry·Gordon LambertusRichard Sacks
Apr 18, 2006·Analytical Chemistry·Shaelah ReidyRichard Sacks
Jul 12, 2007·Journal of Separation Science·Shahab A Shamsi, Neil D Danielson
Sep 28, 2007·Analytical and Bioanalytical Chemistry·Ke HuangDaniel W Armstrong
Nov 1, 2007·Analytical and Bioanalytical Chemistry·John V SeeleyDaniel W Armstrong
Dec 25, 2007·Journal of Chromatography. a·A BerthodS Carda-Broch
Sep 22, 2009·Journal of Chromatography. a·Colin F Poole, Salwa K Poole
Dec 22, 2009·Journal of Chromatography. a·Alastair C LewisMartin J T Milton
May 25, 2012·Journal of Chromatography. a·Carla RagoneseLuigi Mondello
Dec 6, 2012·Journal of Separation Science·Jim LuongHernan J Cortes
Apr 3, 2014·Journal of Chromatography. a·Colin F Poole, Nicole Lenca
May 23, 2015·Lab on a Chip·F HaghighiA Sanati-Nezhad
Feb 9, 2016·Journal of Agricultural and Food Chemistry·Choyce A WeatherlyDaniel W Armstrong
Jul 2, 2016·Journal of Pharmaceutical Sciences·Lillian A Frink, Daniel W Armstrong
Jul 28, 2016·Analytical Chemistry·Lillian A Frink, Daniel W Armstrong
Sep 30, 2017·Journal of Chromatography. a·A BerthodS Carda-Broch
Feb 13, 2018·Analytical and Bioanalytical Chemistry·Cecilia CaglieroBarbara Sgorbini
Feb 20, 2018·Analytical and Bioanalytical Chemistry·Siriluck PojjanapornpunPhilip J Marriott
Jul 19, 2018·Journal of Chromatography. a·Bishnu P RegmiMasoud Agah
Sep 28, 2018·Journal of Separation Science·Rahul A PatilDaniel W Armstrong
Oct 26, 2018·Analytical Chemistry·Bishnu P Regmi, Masoud Agah

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.