Microfluidic platform for environmental contaminants sensing and degradation based on boron-doped diamond electrodes

Biosensors & Bioelectronics
Mariana Medina-SánchezArben Merkoçi

Abstract

We have developed a lab-on-a-chip (LOC) platform for electrochemical detection and degradation of the pesticide atrazine (Atz). It is based on boron-doped diamond (BDD) electrodes and a competitive magneto-enzyme immunoassay (EIA) that enables high sensitivity. To detect the enzymatic reaction, we employed a BDD electrode modified with platinum nanoparticles (PtNPs), as a highly conductive catalytic transducer. Chronoamperometry revealed a limit of detection (LOD) of 3.5 pM for atrazine, which, to the best of our knowledge, is one of the lowest value published to date. Finally, we degraded Atz in the same platform, using a bare BDD electrode that features remarkable corrosion stability, a wide potential window, and much higher O2 overvoltage as compared to conventional electrodes. These characteristics enable the electrode to produce a greater amount of HO• on the anode surface than do conventional electrodes and consequently, to destroy the pollutant more rapidly. Our new LOC platform might prove interesting as a smart system for detection and remediation of diverse pesticides and other contaminants.

References

Oct 28, 2004·Environmental Science & Technology·Alistair B A BoxallSteve J Maund
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May 29, 2010·The Journal of Physical Chemistry. a·Núria BorràsEnric Brillas
Aug 4, 2010·Biosensors & Bioelectronics·Arben Merkoçi
Apr 21, 2012·Lab on a Chip·Mariana Medina-SánchezArben Merkoçi
May 1, 2012·Lab on a Chip·Arben Merkoçi, Jörg P Kutter
Aug 18, 2012·Chemical Reviews·Gemma AragayArben Merkoçi
Dec 1, 2012·Scientific Reports·Stéphane FierroYasuaki Einaga
Oct 1, 2013·Journal of Environmental Management·Augustine Chioma Affam, Malay Chaudhuri

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Citations

Dec 23, 2016·Chemical Communications : Chem Comm·Tribidasari A Ivandini, Yasuaki Einaga
Jul 29, 2017·Chemical Reviews·Zdeněk FarkaPetr Skládal
Aug 23, 2018·Electrophoresis·Tania SierraAlberto Escarpa
May 17, 2019·Advanced Materials·Can DincerFirat Güder
Jan 1, 2020·Nanomaterials·Antonino ScandurraMaria Grazia Grimaldi
Oct 18, 2019·ACS Nano·Carmen C Mayorga-MartinezMartin Pumera

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