Microfluidic synthesis of multifunctional Janus particles for biomedical applications.

Lab on a Chip
Shikuan YangTony Jun Huang

Abstract

Multifunctional Janus particles have a variety of applications in a wide range of fields. However, to achieve many of these applications, high-throughput, low-cost techniques are needed to synthesize these particles with precise control of the various structural/physical/chemical properties. Microfluidics provides a unique platform to fabricate Janus particles using carefully controlled liquid flow in microfluidic channels to form Janus droplets and various types of solidification methods to solidify them into Janus particles. In this Focus article, we summarize the most recent representative works on Janus particle fabrication in microfluidics. The applications of Janus particles in biomedical areas are emphasized. We believe that microfluidics-enabled multifunctional Janus particles could resolve multiple prevalent issues in biomedicine (e.g., disease monitoring at an early stage, high-throughput bioassays, therapeutic delivery) if persistent effort and collaboration are devoted to this direction.

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Citations

Feb 12, 2013·ACS Applied Materials & Interfaces·Chariya KaewsanehaAbdelhamid Elaissari
Mar 14, 2013·ACS Applied Materials & Interfaces·Hiroshi YabuHiroshi Jinnai
Apr 2, 2013·ACS Nano·Yuchao ChenTony Jun Huang
Jan 11, 2014·Lab on a Chip·Yuchao ChenTony Jun Huang
Jun 7, 2014·Lab on a Chip·Nitesh NamaFrancesco Costanzo
May 15, 2013·Lab on a Chip·Yanhui ZhaoTony Jun Huang
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