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Micronized resveratrol shows promising effects in a seizure model in zebrafish and signalizes an important advance in epilepsy treatment

Epilepsy Research

Dec 2, 2019

Laura DecuiAnna Maria Siebel

Abstract

Resveratrol is a natural non-flavonoid polyphenolic that has been emerging in epilepsy treatment. Despite its pharmacological properties, the poor bioavailability of resveratrol has been an important barrier that hinders its application as an anticonvulsant. The aim of this work was to ...read more

Mentioned in this Paper

Anticonvulsants
Epilepsy
Locomotion
Larva
Chemically Induced
Flavonoids
NFAT5 gene
Zebrafish
Diazepam
Analysis
2
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Micronized resveratrol shows promising effects in a seizure model in zebrafish and signalizes an important advance in epilepsy treatment

Epilepsy Research

Dec 2, 2019

Laura DecuiAnna Maria Siebel

PMID: 31786493

DOI: 10.1016/j.eplepsyres.2019.106243

Abstract

Resveratrol is a natural non-flavonoid polyphenolic that has been emerging in epilepsy treatment. Despite its pharmacological properties, the poor bioavailability of resveratrol has been an important barrier that hinders its application as an anticonvulsant. The aim of this work was to ...read more

Mentioned in this Paper

Anticonvulsants
Epilepsy
Locomotion
Larva
Chemically Induced
Flavonoids
NFAT5 gene
Zebrafish
Diazepam
Analysis
2

Similar Papers Found In These Feeds

Angelman Syndrome

Angelman syndrome is a neurogenetic imprinting disorder caused by loss of the maternally inherited UBE3A gene and is characterized by generalized epilepsy, limited expressive speech, sleep dysfunction, and movement disorders. Here is the latest research.

Epilepsy

Epilepsy is a chronic neurological disorder characterized by unprovoked and recurrent seizures. Discover the latest research on factors and mechanisms that underlie epilepsy here.

Related Papers

Scientific Reports

Micronization potentiates curcumin's anti-seizure effect and brings an important advance in epilepsy treatment

Scientific ReportsFebruary 10, 2018
Kanandra Taisa BertoncelloAnna Maria Siebel
Journal of Pharmacological and Toxicological Methods

Validation of the use of zebrafish larvae in visual safety assessment

Journal of Pharmacological and Toxicological MethodsJune 11, 2008
F M RichardsT H Hutchinson
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