PMID: 11909754Mar 23, 2002Paper

Micronuclei in cervical smears and peripheral blood lymphocytes from women with and without cervical uterine cancer

Mutation Research
C H Leal-GarzaElva I Cortés-Gutiérrez

Abstract

Cervical cancer represents the second most common malignant neoplasia in women world-wide. In Mexico, cervical cancer is the most common female malignancy. It has been recently seen an increased frequencies of micronuclei (MN) lymphocytes and cervical epithelial cells of cervical cancer patients. The aim of this hospital-based unmatched case-control study was to investigate the association between progressive stages in development of cervical cancer and frequency of micronucleated cells in the cervical epithelium and peripheral lymphocytes of 40 women, grouped by disease stage. Women at the Obstetrics and Gynecology Hospital of the Instituto Mexicano del Seguro Social (IMSS) in Monterrey, Mexico were diagnosed and classified on the bases of the Papanicolaou (PAP) smear and colposcopy/biopsy into control, low-grade squamous intraepithelial lesions (LGSIL), high-grade squamous intraepithelial lesions (HGSIL), and invasive groups. Analysis of the MN data in both cell types revealed (a) homogeneity among women within each of the four groups with regard to MN frequency, (b) in general, a correlation between MN frequency and grade of cervical lesion, and (c) a positive linear trend between the MN frequency and increased cervical canc...Continue Reading

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Citations

Oct 25, 2012·Journal of Biomedicine & Biotechnology·Elva I Cortés-GutiérrezRicardo M Cerda-Flores
Jan 18, 2013·Journal of Cytology·Bn GayathriB Vasavi
Feb 9, 2010·The Tohoku Journal of Experimental Medicine·Olivera Milosević-DjordjevićDragoslav Marinkoviĉ
Sep 28, 2010·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Noor Ahmad ShaikDurga Koteswara Rao
Apr 22, 2006·Environmental and Molecular Mutagenesis·José Manuel Ornelas-AguirreGuillermo M Zúñiga-González
Jul 2, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Olivera Milošević-DjordjevićSlobodan Arsenijević
May 30, 2013·Electromagnetic Biology and Medicine·Leonardo da Cunha Menezes SouzaJosé Roberto Cardoso Meireles
Feb 9, 2012·International Journal of Dentistry·Lavínia Tércia Magalhães DóreaEneida de Moraes Macílio Cerqueira
Jun 10, 2015·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Rodrigo Pinheiro AraldiRita de Cassia Stocco
Jun 21, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Armen K Nersesyan
Jul 30, 2014·Genetics and Molecular Biology·Ana Paula Rebelo CasselMaria Lucia Rosa Rossetti
Sep 25, 2014·Genetics and Molecular Biology·Caroline Tanski BuenoMaria Lucia Rosa Rossetti
Mar 11, 2009·São Paulo Medical Journal = Revista Paulista De Medicina·Lízia Maria Franco dos Reis CamposEddie Fernando Candido Murta
Oct 30, 2004·Acta Oto-laryngologica·Kayhan OztürkBedri Ozer
Jul 16, 2014·T︠S︡itologii︠a︡ i genetika·E I Cortés-GutiérrezR M Cerda-Flores
Sep 11, 2019·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·E I Cortés-GutiérrezJ Gosálvez
Aug 27, 2005·Carcinogenesis·Andrew J OlaharskiDavid A Eastmond
Apr 1, 2015·Asian Pacific Journal of Cancer Prevention : APJCP·Sivalingam NalliahKumaraswamy Kademane
Feb 25, 2021·Archives of Gynecology and Obstetrics·Elva I Cortés-GutiérrezJaime Gosálvez
Dec 20, 2020·Mutation Research. Reviews in Mutation Research·Richard J Albertini, Debra A Kaden
Jun 5, 2021·Mutation Research. Reviews in Mutation Research·T SetayeshS Knasmueller

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