PMID: 6971840Mar 1, 1981Paper

Micronucleus formation in preimplanted mouse embryos cultured in vitro after irradiation with x-rays and neutrons

International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine
M MollsN Zamboglou

Abstract

Preimplanted mouse embryos cultured in vitro were irradiated with X-rays and neutrons in the late G2-phase of the 2-cell stage. Both radiation qualities induced micronuclei at very low doses. The kinetics of micronucleus formation during the first and second cell cycles after X-irradiation depended on the radiation dose and on the extent of the division delay. New micronuclei appeared to be formed even after the third and later post-irradiation mitoses. The shape of the various dose-effect curves and the mechanism of micronucleus formation by the two radiation qualities are discussed.

References

Feb 1, 1975·Mutation Research·W Schmid
Sep 1, 1979·Mutation Research·M HollsteinW W Nichols
Feb 1, 1978·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·K KretzschmarJ Kutzner
May 1, 1973·Mutation Research·J A Heddle
Dec 1, 1973·Environmental Health Perspectives·R C Miller
Feb 1, 1973·Journal of Theoretical Biology·A V Carrano, J A Heddle
Mar 1, 1980·Cell and Tissue Kinetics·C StrefferS Schulz

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Citations

Nov 1, 1996·International Journal of Radiation Biology·W BöckerC Yu
Aug 1, 1990·International Journal of Radiation Biology·M BaumannH P Beck-Bornholdt
Feb 1, 1991·International Journal of Radiation Biology·U Weissenborn, C Streffer
Jun 6, 1998·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·K WuttkeC Streffer
Jan 1, 1985·Radiation and Environmental Biophysics·U Bertsche
Jan 1, 1981·Radiation and Environmental Biophysics·W U MüllerN Zamboglou
Jan 1, 1984·Radiation and Environmental Biophysics·E K RofstadP Oftedal

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