Micronutrient supplementation in adults with HIV infection.

The Cochrane Database of Systematic Reviews
Marianne E VisserNandi Siegfried

Abstract

Micronutrient deficiencies are common among adults living with HIV disease, particularly in low-income settings where the diet may be low in essential vitamins and minerals. Some micronutrients play critical roles in maintenance of the immune system, and routine supplementation could therefore be beneficial. This is an update of a Cochrane Review previously published in 2010. To assess whether micronutrient supplements are effective and safe in reducing mortality and HIV-related morbidity of HIV-positive adults (excluding pregnant women). We performed literature searches from January 2010 to 18 November 2016 for new randomized controlled trials (RCTs) of micronutrient supplements since the previous review included all trials identified from searches prior to 2010. We searched the CENTRAL (the Cochrane Library), Embase, and PubMed databases. Also we checked the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) and the ClinicalTrials.gov trials registers. We also checked the reference lists of all new included trials. We included RCTs that compared supplements that contained either single, dual, or multiple micronutrients with placebo, no treatment, or other supplements. We excluded studies t...Continue Reading

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Citations

Jan 30, 2018·The Cochrane Database of Systematic Reviews·Marco VincetiCatherine M Crespi
Feb 29, 2020·The Cochrane Database of Systematic Reviews·Parminder S SuchdevLuz Maria De-Regil
Sep 12, 2018·Journal of Clinical Medicine·Zhiyi HuangSong Guo Zheng
May 2, 2018·Current HIV/AIDS Reports·Evelyn Hsieh, Michael T Yin
Aug 4, 2021·Biochimica Et Biophysica Acta. Molecular Basis of Disease·Alfonso MateCarmen M Vázquez

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