Micronutrients and adverse pregnancy outcomes in the context of HIV infection

Nutrition Reviews
Wafaie Fawzi, Gernard Msamanga

Abstract

HIV infection is a global public health problem, particularly in Africa. Concurrently, micronutrient deficiencies and adverse pregnancy outcomes are prevalent in the same settings. Supplements containing B complex and vitamins C and E were efficacious in reducing adverse pregnancy outcomes, including fetal loss, low birth weight, and prematurity among HIV-infected women; the generalizability of this finding to uninfected women is being examined. There is little encouragement from published studies to provide prenatal vitamin A supplements in HIV infection, particularly in light of significantly higher risk of mother-to-child transmission observed in one trial. The efficacy and safety of prenatal zinc and selenium supplements on these outcomes need to be examined in randomized trials.

Citations

Jul 16, 2005·Reproductive Biology and Endocrinology : RB&E·Ashok AgarwalRakesh K Sharma
Apr 19, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Peter Katona, Judit Katona-Apte
Oct 21, 2010·Tropical Medicine & International Health : TM & IH·Lovett LawsonLuis E Cuevas
Feb 19, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Louise C IversMolly F Franke

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