Microphthalmia and linear skin defects syndrome: Precise diagnosis guides prognosis

Pediatric Dermatology
Kerrie G SatcherJennifer J Schoch

Abstract

Microphthalmia and linear skin defects syndrome (MLS) is a rare X-linked dominant disorder characterized by microphthalmia and linear atrophic plaques of the face and neck. The diagnosis of MLS can be challenging secondary to both its rarity and to clinical overlap with Goltz syndrome. Whereas the skin lesions of MLS are more likely to improve in appearance with age, the lesions of Goltz are typically persistent.

References

Oct 28, 2008·Pediatric Dermatology·Vishakha M SharmaSarah L Stein
Nov 6, 2012·American Journal of Human Genetics·Alessia IndrieriBrunella Franco
Mar 10, 2016·Journal of Cutaneous Pathology·Christine J KoJennifer M McNiff
Dec 28, 2016·Pediatric Dermatology·Nicole S GunasekeraSherrie J Divito
Jun 6, 2018·Case Reports in Dermatology·Sahar AlsharifFay Khoja

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