Sep 12, 2014

microRNA biogenesis, degradation and activity in plants

Cellular and Molecular Life Sciences : CMLS
Meng XieBin Yu

Abstract

microRNAs (miRNAs) are important regulators of gene expression. After excised from primary miRNA transcript by dicer-like1 (DCL1, an RNAse III enzyme), miRNAs bind and guide their effector protein named argonaute 1 (AGO1) to silence the expression of target RNAs containing their complementary sequences in plants. miRNA levels and activities are tightly controlled to ensure their functions in various biological processes such as development, metabolism and responses to abiotic and biotic stresses. Studies have identified many factors that involve in miRNA accumulation and activities. Characterization of these factors in turn greatly improves our understanding of the processes related to miRNAs. Here, we review recent progress of mechanisms underlying miRNA expression and functions in plants.

Mentioned in this Paper

Metabolic Process, Cellular
Genes, Plant
Primary MicroRNA
RNA, Small Temporal
AGO1 gene
Gene Expression Regulation, Plant
Gene Expression
Ribonuclease III
CD302 gene
Metabolic Pathway

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