MicroRNA dysregulation interplay with childhood abdominal tumors

Cancer Metastasis Reviews
Karina Bezerra SalomãoMaría Sol Brassesco

Abstract

Abdominal tumors (AT) in children account for approximately 17% of all pediatric solid tumor cases, and frequently exhibit embryonal histological features that differentiate them from adult cancers. Current molecular approaches have greatly improved the understanding of the distinctive pathology of each tumor type and enabled the characterization of novel tumor biomarkers. As seen in abdominal adult tumors, microRNAs (miRNAs) have been increasingly implicated in either the initiation or progression of childhood cancer. Moreover, besides predicting patient prognosis, they represent valuable diagnostic tools that may also assist the surveillance of tumor behavior and treatment response, as well as the identification of the primary metastatic sites. Thus, the present study was undertaken to compile up-to-date information regarding the role of dysregulated miRNAs in the most common histological variants of AT, including neuroblastoma, nephroblastoma, hepatoblastoma, hepatocarcinoma, and adrenal tumors. Additionally, the clinical implications of dysregulated miRNAs as potential diagnostic tools or indicators of prognosis were evaluated.

References

Aug 1, 1992·American Journal of Medical Genetics·L J Hughes, V V Michels
Jan 1, 1991·Pediatrics in Review·A E Brodeur, Garrett M Brodeur
Jan 1, 1993·Medical and Pediatric Oncology·N E BreslowD M Green
Oct 1, 1994·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·D M GreenS Shochat
Feb 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·M J CoppesB R Williams
Mar 4, 2003·Nature Reviews. Cancer·Garrett M Brodeur
Apr 3, 2003·Nature Reviews. Cancer·Ruth EtzioniLeland Hartwell
Aug 27, 2003·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Anil DarbariKathleen B Schwarz
Feb 18, 2004·Nature Reviews. Cancer·Hua Yu, Richard Jove
Feb 20, 2004·Proceedings of the National Academy of Sciences of the United States of America·George A CalinCarlo M Croce
May 12, 2004·Journal of Molecular Biology·Andrea Tanzer, Peter F Stadler
Mar 15, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P AnsellT O B Eden
Jul 19, 2005·Nature Reviews. Molecular Cell Biology·Barry M Gumbiner
Aug 3, 2005·Nature Reviews. Molecular Cell Biology·Sovana Adhikary, Martin Eilers
Oct 28, 2005·The New England Journal of Medicine·Chang-Zheng Chen
Jan 6, 2007·Biochemical and Biophysical Research Communications·Valia BravoRicardo L Pastori
Mar 21, 2007·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Angela B MariottoEric J Feuer
Apr 12, 2007·Archives of Pathology & Laboratory Medicine·Milton J FinegoldCollege of American Pathologists
May 19, 2007·Science·Michael B MajorRandall T Moon
Dec 13, 2007·Cancer·Amy M Linabery, Julie A Ross
Jan 15, 2008·Cell·Ana EulalioElisa Izaurralde
Jan 26, 2008·Clinical Chemistry·Stephen S C ChimY M Dennis Lo
May 28, 2008·Oncogene·J S WeiJ Khan
May 29, 2008·Molecular Cancer Research : MCR·Kristina A ColeJohn M Maris
Jun 4, 2008·Cancer Research·Eric J KortBin T Teh
Jul 10, 2008·The Journal of Clinical Endocrinology and Metabolism·Madson Q AlmeidaAna Claudia Latronico
Jul 30, 2008·Proceedings of the National Academy of Sciences of the United States of America·Patrick S MitchellMuneesh Tewari
Aug 12, 2008·Biochemical and Biophysical Research Communications·Cliff Ji-Fan LinJen-Leih Wu
Oct 17, 2008·PloS One·Ming LuQinghua Cui
Oct 29, 2008·Genome Research·Robin C FriedmanDavid P Bartel
Jun 2, 2009·Nature Genetics·Srinivas R ViswanathanGeorge Q Daley
Aug 4, 2009·The International Journal of Biochemistry & Cell Biology·C ArmengolMarie-Annick Buendia
Aug 25, 2009·Translational Oncology·Armando MagrelliDomenica Taruscio
Sep 23, 2009·Biochemical and Biophysical Research Communications·M MrazS Pospisilova
Oct 2, 2009·Journal of Gastroenterology and Hepatology·Qiong LiDong Wang
Jan 19, 2010·Proceedings of the National Academy of Sciences of the United States of America·Hailiang HuRichard A Gatti
Jan 19, 2010·Proceedings of the National Academy of Sciences of the United States of America·Jakob LovénMarie Henriksson
Apr 15, 2010·Cancer Research·Angelo VeroneseMassimo Negrini
Apr 22, 2010·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Patrick G BuckleyRaymond L Stallings
May 13, 2010·Molecular Cancer Research : MCR·Erin C ConnollyCharles E Rogler
May 15, 2010·Nucleic Acids Research·Johannes H SchulteAlexander Schramm
May 18, 2010·International Journal of Cancer. Journal International Du Cancer·Johannes H SchulteAlexander Schramm
Jul 14, 2010·Molecular Carcinogenesis·Ruey-Jen LinAlice L Yu
Sep 3, 2010·Pediatric Surgery International·Tetsuya YamagataTakao Ohki
Oct 14, 2010·Molecular Cancer Therapeutics·Kristi E Allen, Glen J Weiss
Nov 10, 2010·Proceedings of the National Academy of Sciences of the United States of America·Stefano CairoMarie-Annick Buendia
Nov 26, 2010·Molecular and Cellular Endocrinology·Abeer El WakilEnzo Lalli
Jan 15, 2011·Cell Death and Differentiation·E A AfanasyevaFrank Westermann
Jan 27, 2011·BMC Cancer·A TivnanRaymond L Stallings
Feb 12, 2011·Cancer Letters·Isabella BrayRaymond L Stallings
Feb 15, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Julia von FroweinIrene Schmid
Mar 9, 2011·Proceedings of the National Academy of Sciences of the United States of America·Jason D ArroyoMuneesh Tewari
Jun 8, 2011·Nature Reviews. Clinical Oncology·Maria Angelica CortezGeorge A Calin
Jul 19, 2011·Biochemical and Biophysical Research Communications·Chun-Mei WangJi-Hui Jia
Jul 29, 2011·International Journal of Cancer. Journal International Du Cancer·Sara De BrouwerFrank Speleman
Oct 25, 2011·Molecular and Cellular Endocrinology·André M Faria, Madson Q Almeida
Dec 6, 2011·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Rachel PurcellMichael Sullivan
Dec 14, 2011·Oncology Reports·Lin FangGuang-Shun Yang
Jan 17, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Rudolf MaibachGiorgio Perilongo
Jan 27, 2012·Liver International : Official Journal of the International Association for the Study of the Liver·Jie XuFusheng Wu
Feb 18, 2012·Nature·Amaia Lujambio, Scott W Lowe
Apr 25, 2012·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Qing-jun LiKe-feng Dou
Jun 14, 2012·Pediatric Blood & Cancer·Logan G Spector, Jill Birch
Aug 9, 2012·BMC Genomics·Jana SchmittEckart Meese
Aug 14, 2012·Cell Biochemistry and Function·Wang WeiZhao Jisheng
Sep 4, 2012·Biochemical and Biophysical Research Communications·Qingbo Lang, Changquan Ling
Sep 5, 2012·Trends in Biochemical Sciences·Andrey TurchinovichBarbara Burwinkel
Oct 23, 2012·Journal of Pediatric Surgery·Yun ChenSheng-Hong Tseng
Nov 24, 2012·Nature Reviews. Cancer·Paul A NorthcottStefan M Pfister
Dec 18, 2012·Molecular Medicine Reports·Aimei LiFengmin Zhang
Dec 21, 2012·Pediatric Blood & Cancer·Carlos Rodriguez-GalindoCOG Rare Tumors Disease Committee
Jan 12, 2013·PloS One·Jenny A WatsonMaureen J O'Sullivan
Mar 29, 2013·The New England Journal of Medicine·H L JanssenMichael R Hodges
Apr 5, 2013·Immunological Reviews·Chang-Zheng ChenChristina Loh
Apr 6, 2013·Cancer Epidemiology·Julia E HeckBeate Ritz
Apr 19, 2013·Journal of Experimental & Clinical Cancer Research : CR·Ming-Qi FanLin Zhong
Apr 20, 2013·International Journal of Molecular Sciences·Xiangxiang ShanFen Zhou
Apr 27, 2013·The Journal of Pathology·M K WuWilliam D Foulkes
Apr 30, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Xin-Jun WuMing-Hui Xue
Apr 30, 2013·Cell·Luke A YatesRobert J C Gilbert
Apr 30, 2013·Nucleic Acids Research·Marco LodriniHedwig E Deubzer
May 1, 2013·Genes, Chromosomes & Cancer·Karin KollerBarbara Guertl
Jun 4, 2013·Liver International : Official Journal of the International Association for the Study of the Liver·Yun ZhouJianping Zhang
Jun 4, 2013·Nanomedicine : Nanotechnology, Biology, and Medicine·Shu-Hao HsuKalpana Ghoshal
Jun 21, 2013·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Julie Bienertová-VaškůOndrej Slaby
Aug 21, 2013·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Kimberly J JohnsonLogan G Spector
Aug 22, 2013·Biochemical and Biophysical Research Communications·Jian WangWeidong Ma
Sep 7, 2013·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Dolores Lopez-TerradaMilton J Finegold
Sep 13, 2013·Journal of Clinical Neonatology·Jyotindu DebnathAniruddha Pandit
Sep 27, 2013·Nucleic Acids Research·Luca F R GebertJonathan Hall
Nov 5, 2013·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Bo GaoLi Lin
Nov 8, 2013·The New England Journal of Medicine·Carrie L WilliamsAlastair G Sutcliffe
Nov 14, 2013·PloS One·Galina Feinberg-GorenshteinSmadar Avigad
Dec 11, 2013·Current Opinion in Pediatrics·Piotr CzaudernaRebecka L Meyers
Jan 2, 2014·Molecular and Cellular Biochemistry·Qingliang ZhengYaozhou Zhang
Feb 13, 2014·Oncology Letters·Lin ChengJianwen Gu
Feb 27, 2014·Virchows Archiv : an International Journal of Pathology·Mónika GyugosAndrás Kiss
Feb 27, 2014·Frontiers in Molecular Neuroscience·Philipp FollertChristophe Béclin
Mar 13, 2014·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Karin KollerBarbara Guertl
Apr 16, 2014·Genes & Development·Achia UrbachGeorge Q Daley
Apr 25, 2014·Current Opinion in Pediatrics·Nathalie KremerGregory M Tiao
Apr 29, 2014·Marine Pollution Bulletin·Suraia NusrinRichard Y C Kong
Jun 6, 2014·Genes, Chromosomes & Cancer·Irene Y CheungNai-Kong V Cheung
Jun 10, 2014·Nature Communications·Giovana T TorrezanDirce M Carraro
Jun 11, 2014·Molecular & Cellular Proteomics : MCP·Pasqualino De AntonellisMassimo Zollo
Jun 14, 2014·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Chunhui CuiZonghai Huang
Jun 17, 2014·Cancer Medicine·Charles-Henry GattolliatSétha Douc-Rasy
Jun 28, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Shun-Li GaoZhi-Wei Zhang
Jul 2, 2014·Proceedings of the National Academy of Sciences of the United States of America·Jingwen WuWei Yan
Jul 12, 2014·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Yu LiYong-Ming Li
Jul 17, 2014·Nature Reviews. Molecular Cell Biology·Minju Ha, V Narry Kim
Jul 22, 2014·International Journal of Cancer. Journal International Du Cancer·Kristina AlthoffJohannes H Schulte
Aug 5, 2014·Acta Pharmacologica Sinica·Yue WangLihong Ye
Aug 12, 2014·Cellular and Molecular Life Sciences : CMLS·Garyfallia PapaioannouTatsuya Kobayashi
Aug 20, 2014·International Journal of Cancer. Journal International Du Cancer·Harry HarveyIsabella Bray
Sep 2, 2014·Nature Reviews. Cancer·William D FoulkesThomas F Duchaine
Sep 30, 2014·Applied Immunohistochemistry & Molecular Morphology : AIMM·Meora FeinmesserYael Spector
Oct 9, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Li WangMing-Hui Zhu
Oct 10, 2014·Cellular and Molecular Life Sciences : CMLS·Peter IgazKároly Rácz
Oct 15, 2014·Journal of the National Cancer Institute·Benjamin GibertPatrick Mehlen
Nov 14, 2014·Clinical Chemistry·Kenneth W Witwer
Nov 25, 2014·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Matthew J MurrayNicholas Coleman
Dec 3, 2014·Biochimica Et Biophysica Acta·Maša Alečković, Yibin Kang
Feb 5, 2015·Epigenomics·Lu Qian Wang, Chor Sang Chim
Feb 18, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Shuxiang HuYuzhen Gao
Mar 20, 2015·Pediatric Blood & Cancer·Nicole LudwigEckart Meese
Mar 26, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Hui LiuXueying Long
Mar 27, 2015·Mini Reviews in Medicinal Chemistry·Bridget Simonson, Saumya Das
Mar 31, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Kuang-Hsiang ChuangChristopher T Barry
Apr 19, 2015·Oncotarget·Guixing JiangLiping Cao
Apr 22, 2015·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Liang ShiXiangyang Lin
Apr 30, 2015·Clinics in Liver Disease·Deirdre KellyBruce Morland
May 9, 2015·Circulation Research·Conrad P HodgkinsonVictor J Dzau
May 15, 2015·Computational and Structural Biotechnology Journal·Duncan AyersJo Vandesompele
Jun 19, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Wei GuoChangjun Wang
Jul 8, 2015·Molecular Medicine Reports·Bijing MaoGe Wang
Jul 11, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Wei ZhangYahui Liu
Aug 1, 2015·World Journal of Gastroenterology : WJG·Liliana ChioreanChristoph F Dietrich
Sep 2, 2015·Molecular Medicine Reports·Hongyan HuangShaoyang Li
Sep 18, 2015·World Journal of Gastroenterology : WJG·Yu-Cheng ZhangYa-Li Wang
Oct 20, 2015·Breast Cancer Research and Treatment·Lei ZhangZicai Liang
Nov 10, 2015·Biochemical and Biophysical Research Communications·Zhanping LuXiao-Dong Zhang
Nov 20, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Jianting LongMing Kuang
Nov 21, 2015·Journal of Controlled Release : Official Journal of the Controlled Release Society·Justyna M MeissnerAleksander F Sikorski
Nov 22, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Wen-Fang LiChang-An Liu
Nov 30, 2015·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Wei DingLan Wang
Jan 19, 2016·International Journal of Biological Macromolecules·Sen LuXinli Huang
Feb 26, 2016·Indian Journal of Cancer·S KhannaV K Shukla
Mar 18, 2016·Oncology Reports·Enrica FabbriRoberto Gambari
Mar 25, 2016·Cancer Control : Journal of the Moffitt Cancer Center·Yaodong Zhou, Bo Sheng
Apr 20, 2016·Experimental Cell Research·Zhijie TianXiaozhen Dai
Apr 30, 2016·International Journal of Molecular Sciences·Erika LarreaCharles H Lawrie
Jul 20, 2016·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Zuoqing LiLi Zhou
Aug 6, 2016·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Min ZhuBenyan Wu
Sep 20, 2016·Biochemical and Biophysical Research Communications·Wenxian CuiZhirong Kang
Oct 19, 2016·Biochimica Et Biophysica Acta·Federica ParodiBarbara Banelli
Nov 30, 2016·Experimental Biology and Medicine·Subodh KumarAnuradha Chakraborti
Dec 8, 2016·Methods in Molecular Biology·Marco F Schmidt
Dec 22, 2016·Biochemical and Biophysical Research Communications·Zheng DongYinying Lu
Dec 23, 2016·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Xiao-Yan HeLin Zou
Jan 21, 2017·Oncology Letters·Chengyong LiuHaibin Huang
Jan 27, 2017·Oncology Letters·Dianguo LiXiaogang Sun
Feb 2, 2017·Journal of Hepatocellular Carcinoma·Irene Schmid, Dietrich von Schweinitz
Apr 13, 2017·Chinese Medical Sciences Journal = Chung-kuo I Hsüeh K'o Hsüeh Tsa Chih·Xiufen ZhangLihua Li
May 13, 2017·Molecular Medicine Reports·Liyi HongHong Zhu
May 23, 2017·The Tohoku Journal of Experimental Medicine·Mingyu CuiRongde Wu
Jun 7, 2017·Oncology Reports·Francesca MegiorniCarlo Dominici
Jun 8, 2017·Experimental and Therapeutic Medicine·Feng XueBoqing Wang
Jun 25, 2017·Scientific Reports·Jing WangXiaoyi Huang
Jul 24, 2017·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Kun ZhouGang Sun
Jul 29, 2017·Clinics and Research in Hepatology and Gastroenterology·Hamdy E Abouzeid AliAbdel Hady Abdel Wahab
Aug 31, 2017·International Journal of Endocrinology·Stacy RobertsonEleanor Davies
Aug 31, 2017·Iranian Journal of Basic Medical Sciences·Liang WangChangao Xie
Sep 10, 2017·Molecular and Cellular Biochemistry·Annie ZhangBrian G Harbrecht
Sep 26, 2017·Journal of Genomics·Srinivas V KoduruDino J Ravnic
Oct 14, 2017·Cancer Genetics·Ayda ArabKambiz Sheikhy
Dec 27, 2017·Journal of Cellular Biochemistry·Min ShiXiao-Jie Lu
Jan 10, 2018·Liver International : Official Journal of the International Association for the Study of the Liver·Julia von FroweinIrene Schmid
Jan 14, 2018·Endocrine-related Cancer·Michael SolarskiKalman Kovacs
Jan 16, 2018·Technology in Cancer Research & Treatment·Hui TangWei Meng
Jan 18, 2018·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Kazunori WatanabeTakashi Ohtsuki
Jan 27, 2018·Indian Journal of Clinical Biochemistry : IJCB·Shaymaa M M YahyaHeba K Nabih
Jan 30, 2018·F1000Research·Piotr Czauderna, Hanna Garnier
Feb 7, 2018·Hepatology Communications·Emilie IndersieChristophe F Grosset
Feb 14, 2018·Pediatrics in Review·Wendy Allen-RhoadesNino Rainusso
Mar 3, 2018·OncoTargets and Therapy·Xiuyun Jiang, Huaicheng Li
Mar 9, 2018·International Journal of Cancer. Journal International Du Cancer·Claire AgostaNadia Cherradi
Mar 24, 2018·Molecular Medicine Reports·Shichang CuiQidong Sun
Mar 31, 2018·International Journal of Molecular Sciences·Francesca PezzutoMaria Lina Tornesello
Apr 6, 2018·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Hongdan LiZhen Ren
May 5, 2018·Pathology, Research and Practice·Yizhou WangRenyan Gong
May 8, 2018·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Guoyong HanXuehao Wang
Jun 12, 2018·Journal of Pediatric Hematology/oncology·Çiğdem Ö EcevitNur Olgun
Jun 29, 2018·BioMed Research International·Erbao ChenTianshu Liu
Jul 20, 2018·Clinical & Experimental Metastasis·Stanley P LeongMojca Skoberne
Aug 31, 2018·Non-coding RNA Research·Grace T KwokStan B Sidhu
Dec 7, 2018·JCI Insight·Fjoralba ZekaJo Vandesompele
Feb 5, 2019·European Journal of Pharmacology·Xinru ChengQian Zhang
Feb 6, 2019·European Review for Medical and Pharmacological Sciences·X-Y CaoB Yuan
Feb 17, 2019·Cellular and Molecular Life Sciences : CMLS·Aroa SorianoMiguel F Segura
Feb 25, 2019·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Kai LiuShuya Wang
May 23, 2019·European Review for Medical and Pharmacological Sciences·C ZhangQ-E Liu
Jul 23, 2019·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Yihang GongJian Li
Dec 4, 2019·Clinical and Experimental Pharmacology & Physiology·Jun WangQingguang Liu

Citations

Jan 7, 2021·Cancer Metastasis Reviews·Irfete S Fetahu, Sabine Taschner-Mandl

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biopsy
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surgical resection
xenografts
transfection

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