microRNA expression in erythropoiesis and erythroid disorders

British Journal of Haematology
Charles H Lawrie

Abstract

MicroRNAs are a recently discovered class of small (c. 22 nt) naturally occurring non-coding RNA molecules that regulate gene expression through binding to the un-translated region of target mRNA. MicroRNAs play key roles in many cellular pathways including haematopoiesis and aberrant expression is a common feature of haematological malignancies. Whilst other areas of haematopoiesis have been extensively reviewed the involvement of microRNAs in red cell production (erythropoiesis) and disorders of this pathway is lacking. In this review the rapidly accumulating evidence that points to the major role microRNAs play in both erythropoiesis and erythroid disorders is discussed.

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Citations

Apr 30, 2013·Blood Cells, Molecules & Diseases·Orawan SarakulTsukuru Umemura
Jul 24, 2013·The International Journal of Biochemistry & Cell Biology·Smriti P K MittalSamit Chattopadhyay
Sep 8, 2018·Journal of Cellular Physiology·Mahjoobeh JafariHaleh Akhavan-Niaki
Jun 25, 2019·Frontiers in Genetics·Khuthala MnikaAmbroise Wonkam
Feb 23, 2020·Frontiers in Immunology·Kehinde Adebayo BabatundePierre-Yves Mantel
Jan 6, 2021·Annals of Hematology·Henu Kumar VermaRaffaella Colombatti
Apr 1, 2021·Journal, Genetic Engineering & Biotechnology·Noha Hamdy EltaweelKhalda S Amr

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