MicroRNA-induced drug resistance in gastric cancer

Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie
Rashedeh DehghanzadehMehdi Yousefi

Abstract

Drug resistance remains one of the major reasons of therapy failure in gastric cancer patients. Although the mechanisms of anticancer drug resistance have been broadly investigated, they have not been completely understood. Accumulating reports have recently highlighted the involvement of endogenous non-coding RNAs, known as microRNAs, in the evolution of cancer cell drug resistance. MiRNAs have been characterized as major regulators of crucial genes implicated in the chemoresistance phenotype of gastric cancer cells. MiRNA-based therapy in the future may provide a new strategy to overcome drug resistance. This review summarizes the current knowledge on the role of miRNAs in regulating drug resistance in gastric cancer and their potential to develop targeted therapies and personalized treatment for managing drug resistant gastric cancers.

References

Mar 10, 2005·International Journal of Cancer. Journal International Du Cancer·Changcun GuoDaiming Fan
May 26, 2005·Proceedings of the National Academy of Sciences of the United States of America·Roman RouzierLajos Pusztai
Jul 19, 2005·Cancer Research·Jennifer A ChanKenneth S Kosik
Mar 15, 2006·Cancer Cell·Nozomu YanaiharaCurtis C Harris
Apr 13, 2006·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Liu HongDaiming Fan
May 3, 2006·Biological & Pharmaceutical Bulletin·Yukihiro AkaoTomoki Naoe
Jul 11, 2006·The New England Journal of Medicine·David Cunningham MAGIC Trial Participants
Oct 4, 2006·EMBO Reports·Brendan P EckelmanFiona L Scott
Oct 31, 2006·Oncogene·M-L SiY-Y Mo
Apr 18, 2007·Genes & Development·Yong Sun Lee, Anindya Dutta
Jun 2, 2007·Molecular Cell·Nina Raver-ShapiraMoshe Oren
Jun 2, 2007·Molecular Cell·Tsung-Cheng ChangJoshua T Mendell
Jul 10, 2007·Cancer Research·Weng-Onn LuiAndrew Fire
Jul 28, 2007·Current Biology : CB·Guido T BommerEric R Fearon
Oct 19, 2007·Cancer Research·Valerie B SampsonLeslie J Krueger
Jan 19, 2008·Nature Reviews. Cancer·Anthony G Letai
Mar 1, 2008·Proceedings of the National Academy of Sciences of the United States of America·Madhu S KumarTyler Jacks
Apr 29, 2008·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C Gravalos, A Jimeno
May 2, 2008·International Journal of Cancer. Journal International Du Cancer·Lin XiaDaiming Fan
Jan 30, 2009·Journal of Gastroenterology and Hepatology·Junming GuoYanjun Wang
May 23, 2009·Cell Death and Differentiation·H Hermeking
Jul 28, 2009·International Journal of Cancer. Journal International Du Cancer·Tongsen ZhengLianxin Liu
Nov 11, 2009·Journal of Cellular and Molecular Medicine·Wang RuiChen Long-Bang
Jan 20, 2010·Technology in Cancer Research & Treatment·Mei MeiZhi Yao
Jan 26, 2010·International Journal of Cancer. Journal International Du Cancer·Igor P PogribnyOlga Kovalchuk
Feb 18, 2010·International Journal of Cancer. Journal International Du Cancer·Wei ZhuPing Liu
May 15, 2010·Cancer Gene Therapy·J MaC Ji
Sep 3, 2010·Cancer Research·Andreas G BaderMatthew Winkler
Sep 3, 2010·Annual Review of Pharmacology and Toxicology·Michela Garofalo, Carlo M Croce
Oct 14, 2010·Molecular Cancer Therapeutics·Kristi E Allen, Glen J Weiss
Jan 7, 2011·Expert Opinion on Therapeutic Targets·Paolo GandelliniNadia Zaffaroni

❮ Previous
Next ❯

Citations

Feb 24, 2016·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Maryam HemmatzadehMehdi Yousefi
Jan 24, 2017·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Hengchun ZhangHao Jiang
Aug 26, 2017·Expert Review of Gastroenterology & Hepatology·Wanli YangLiu Hong
Dec 18, 2018·Journal of Cellular Biochemistry·Solmaz ShirjangMehdi Yousefi
Apr 4, 2019·Journal of Cellular Physiology·Wei FengShaoqing Ju
Mar 22, 2019·International Journal of Oncology·Chao ChenJingjing Liu
Nov 30, 2019·Current Drug Targets·Liudmila V SpirinaEvgeny A Usynin
Sep 24, 2020·Molecular and Cellular Biochemistry·Yongxian CaoHuazheng Pan
Dec 7, 2018·Journal of Cellular Biochemistry·Afshin NikkhooFarhad Jadidi-Niaragh
May 26, 2016·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Bo-Chuan LinFeng-Jun Shi
Apr 15, 2017·Journal of Experimental & Clinical Cancer Research : CR·Peiming ZhengLisong Shen
Oct 26, 2018·Sensors·Elisabetta PrimiceriGiuseppe Maruccio
Nov 8, 2018·Journal of Experimental & Clinical Cancer Research : CR·Ke-Ting QueZuo-Jin Liu
Oct 16, 2018·International Journal of Oncology·Haijin HuangXiaoyu Zhang
Dec 5, 2019·World Journal of Gastrointestinal Oncology·Ya-Jun LuoJiang-Wei Xiao
Jun 5, 2020·Cellular Oncology (Dordrecht)·Arash PoursheikhaniSadegh Babashah
Jun 6, 2018·Journal of Experimental & Clinical Cancer Research : CR·Li-Dong ZuGuo-Hui Fu
Aug 9, 2020·OncoTargets and Therapy·Tonghua DuBin Liu
Oct 30, 2020·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Hui ZhangQi Zhou
Dec 31, 2017·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Adel NaimiSaeed Solali

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved